Descriptive analysis of recurrences of nasal intestinal‐type adenocarcinomas after radiotherapy

paythelady.61 shared this article with you from Inoreader Descriptive analysis of recurrences of nasal intestinal‐type adenocarcinomas after radiotherapy Via Head & Neck Abstract Background Despite adjuvant radiotherapy, rates of recurrences of endoscopically operated nasal intestinal-type adenocarcinomas (ITAC) have not been improved in successive series. To better understand how to improve local control, we aimed to investigate the site of local recurrences of ITACs. Methods Retrospective study in a reference center in sinonasal malignancies. For all patients with a local recurrence, radiotherapy plans were retrieved and compared to the delineation of local recurrences. Results Of 63 patients, 54 underwent adjuvant radiotherapy of which 14 (25.9%) had a local recurrence. Eleven of them had their onset in an optimally irradiated area. Difficulty to dissect the cribriform plate and/or the lateral lamina was reported for 11 patients with local recurrences in the operative reports (p <0.0001). Conclusions Most of recurrences arose in an optimally irradiated area. A close cooperation between surgeons and radiotherapists is required to define areas at risk and adapt treatment. View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.

Key Issues in Use of Prophylactic Steroids to Prevent Hypocalcemia and Voice Dysfunction After Thyroidectomy—Reply

paythelady.61 shared this article with you from Inoreader Key Issues in Use of Prophylactic Steroids to Prevent Hypocalcemia and Voice Dysfunction After Thyroidectomy—Reply Via JAMA Otolaryngology–Head & Neck Surgery Online First In Reply We thank Ms Kane and colleagues for their feedback on our article. View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.

Expert consensus on dental caries management

paythelady.61 shared this article with you from Inoreader Expert consensus on dental caries management Via International Journal of Oral Science - Issue International Journal of Oral Science, Published online: 31 March 2022; doi:10.1038/s41368-022-00167-3 Expert consensus on dental caries management View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.

The implicated clinical factors for outcomes in 304 patients with salivary duct carcinoma: Multi‐institutional retrospective analysis in Japan

paythelady.61 shared this article with you from Inoreader The implicated clinical factors for outcomes in 304 patients with salivary duct carcinoma: Multi‐institutional retrospective analysis in Japan Via Head & Neck Abstract Background Salivary duct carcinoma (SDC) is a high-grade salivary malignancy that frequently occurs as the carcinomatous component of carcinoma ex pleomorphic adenoma. We herein examined the clinical factors affecting outcomes in a large cohort of SDC. Methods We selected 304 SDC cases and investigated clinical characteristics and the factors affecting outcomes. Results The median age of the cases examined was 68 years, the most common primary site was the parotid gland (238 cases), and there was a male predominance (M/F = 5:1). Outcomes were significantly worse when the primary tumor site was the minor salivary glands (SG) than when it was the major SG. Outcomes were also significantly worse in pN(+) cases (161 cases) than in pN0 cases, particularly those with a metastatic lymph node number ≥11. The cumulative incidence of relapse and distant metastases was significantly higher in stage IV cases than in stage 0–III cases. Conclusions The absolute number of lymph node metastases, higher stages, and the minor SG as the primary tumor site were identified as factors affecting the outcome of SDC. View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.

Subclonal heterogeneity sheds light on the transformation trajectory in IGLV3-21R110 chronic lymphocytic leukemia

paythelady.61 shared this article with you from Inoreader Subclonal heterogeneity sheds light on the transformation trajectory in IGLV3-21<sup>R110</sup> chronic lymphocytic leukemia Via Blood Cancer Journal - Issue - nature.com science feeds View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.

From a Slave to a Surgeon: David Kearney McDonogh, the First Black Otolaryngologist

paythelady.61 shared this article with you from Inoreader From a Slave to a Surgeon: David Kearney McDonogh, the First Black Otolaryngologist Via SAGE-Journals: Otolaryngology-Head and Neck Surgery: Table of Contents Otolaryngology–Head and Neck Surgery, Ahead of Print. David McDonogh, born into chattel slavery in Louisiana in the early 1800s, accomplished the unfathomable by becoming the first Black otolaryngologist in the United States of America. With tireless determination and profound intellect, Dr McDonogh surmounted immeasurable adversity along his improbable journey to freedom and success as an eye, ear, nose, and throat doctor in New York. His doctorate in medicine was posthumously awarded to his great-great-granddaughter in 2018 by the Columbia University Vagelos College of Physicians and Surgeons. In this History of Otolaryngology piece, we share his extraordinary story. View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.

Subclonal heterogeneity sheds light on the transformation trajectory in IGLV3-21R110 chronic lymphocytic leukemia

paythelady.61 shared this article with you from Inoreader Subclonal heterogeneity sheds light on the transformation trajectory in IGLV3-21<sup>R110</sup> chronic lymphocytic leukemia Via Blood Cancer Journal - Issue - nature.com science feeds Blood Cancer Journal, Published online: 30 March 2022; doi:10.1038/s41408-022-00650-4 Subclonal heterogeneity sheds light on the transformation trajectory in IGLV3-21R110 chronic lymphocytic leukemia View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.

Comparison of the Osteogenic Effectiveness of an Autogenous Demineralized Dentin Matrix and Bio-Oss® in Bone Augmentation: A Systematic Review and Meta-analysis

paythelady.61 shared this article with you from Inoreader Comparison of the Osteogenic Effectiveness of an Autogenous Demineralized Dentin Matrix and Bio-Oss® in Bone Augmentation: A Systematic Review and Meta-analysis Via British Journal of Oral and Maxillofacial Surgery Publication date: Available online 29 March 2022 Source: British Journal of Oral and Maxillofacial Surgery Author(s): Yanfei Li, Wanhang Zhou, Peiyi Li, Qipei Luo, Anqi Li, Xinchun Zhang View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.

Anatomical variations in the relationship between the spinal accessory nerve and internal jugular vein: a systematic review and meta-analysis

paythelady.61 shared this article with you from Inoreader Anatomical variations in the relationship between the spinal accessory nerve and internal jugular vein: a systematic review and meta-analysis Via International Journal of Oral and Maxillofacial Surgery The relationship between the spinal accessory nerve and internal jugular vein is important for modified neck dissection surgery. Therefore, the aim of this review was to investigate variations in this relationship. Through a search of the PubMed, Scopus, Web of Science, LILACS, and SciELO databases, the review authors collected anatomical data for inclusion in a meta-analysis, following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines. Four relationship patterns were identified and classified: type 1, the nerve lies superficial to the vein; type 2, the nerve lies deep to the vein; type 3, the nerve crosses the branches of the vein; type 4, the nerve splits and its branches pass around the vein. View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.

Fibrin immobilization vestibular extension (FIVE): A case series

paythelady.61 shared this article with you from Inoreader Fibrin immobilization vestibular extension (FIVE): A case series Via Clinical Implant Dentistry and Related Research Abstract Aims The objective of the present case series is to report on the rationale, surgical technique and outcome of a protocol for peri-implant mucosal phenotype modification therapy, referred to as "fibrin immobilization vestibular extension (FIVE)". Material and Methods The protocol utilized entailed apical positioning and stabilization of peri-implant flap with modular screws. The screws were also used for the immobilization of solid matrix platelet-rich fibrin to fill the gap created between apically positioned flap and the crestal margin of the flap. Results A total of 30 patients (12 male, 18 females) with 93 implants were treated with FIVE protocol for various indications, including for vestibular extension following alveolar ridge augmentation (N = 6), preprosthetic (N = 9), postprosthetic (N = 2), and peri-implantitis (N = 13). The keratinized mucosal width preoperatively was 1.67 mm with 95% confidence interval [CI] (1.46, 1.88). Immediately following FIVE surgery, the vestibule was extended to 9.10 with 95% CI (8.44, 9.76). At 3 months, 4.9 mm (95% CI: 4.5–5.2 mm) of peri-implant keratinized mucosal width was present. The keratinized mucosal width remained relatively stable thereafter and was 4.0 mm (95% CI: 3.5–4.5 mm) at 3 years post-FIVE surgery. When overall group means across all time points were analyzed, maxilla had mean of 6.1 mm (95% CI: 5.8–6.5) versus mandible exhibited mean of 5.1 mm (95% CI: 4.6–5.6 mm). The mean of maxilla was si gnificantly higher than that of the mandible (p < 0.0001) across all time points. Treatment of peri-implantitis with FIVE lead to significant pocket reduction and wide band of keratinized mucosa. Seven of 38 implants in 3 of 13 peri-implantitis patients were removed due to advanced peri-implantitis. Discussion The present case series provides proof-of-principle data for efficacy of FIVE for peri-implant phenotype modification therapy that generated attached keratinized mucosa in a variety of applications. This protocol provides an alternative to procedures involving harvesting of autogenous mucosal graft. View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.

Migration of a Fish Bone From the Esophagus to the Thyroid Gland

a.sfakia shared this article with you from Inoreader Migration of a Fish Bone From the Esophagus to the Thyroid Gland Via ear nose throat Ear Nose Throat J. 2022 Mar 29:1455613221086032. doi: 10.1177/01455613221086032. Online ahead of print. ABSTRACT Accidental swallowing of fish bone is one of the most common emergencies in the otolaryngology department. The impacted fish bones are usually found in the palatine tonsil, base of the tongue, valleculae, pyriform sinus, and esophagus, which can be successfully removed after a thorough examination. However, in some cases, the fish bone may penetrate into the neck soft tissue and migrate to extraluminal organs, causing infection, abscess formation, or rupture of vessels. In such cases, prompt recognition and immediate removal of the impacted fish bone are necessary. Herein, we report a rare case of a 60-year-old woman who had accidently swallowed a fish bone 10 days prior to visiting the outpatient department. The fiberoptic scope and head and neck computed tomography scans were obtained from the outpatient department. The fish bone was found to migrate from the upper esophagus to the left thyroid gland. First, a rigid esophageal endoscopy was performed in the operating room, but no obvious fish bone was noted over the esophagus. Finally, the fish bone was removed via exploratory cervicotomy with left-sided total lobectomy of the thyroid. The patient recovered after the operation, and there were no further complications during the 3 years of follow-up. PMID:35348022 | DOI:10.1177/01455613221086032 View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.

A comparison between sniffing and blowing for olfactory testing before and after laryngectomy

a.sfakia shared this article with you from Inoreader A comparison between sniffing and blowing for olfactory testing before and after laryngectomy Via http://link.springer.com/journal/405,European archives of oto-rhino-laryngology,The European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino Eur Arch Otorhinolaryngol. 2022 Mar 29. doi: 10.1007/s00405-022-07343-5. Online ahead of print. ABSTRACT PURPOSE: Olfactory dysfunction occurs after laryngectomy due to the loss of nasal airflow and inability to sniff. However, the reason for the loss of olfactory function after laryngectomy is unclear on evaluation with sniffing type tests performed individually. It is expected that the sensorineural olfaction remains, and the results of the sniffing test would be negative, while that of the odour-blowing test would be positive. Therefore, the aim of this study was to investigate both tests and prove normal olfaction in the patients. METHODS: Patients who had undergone laryngectomy were evaluated using the T&T olfactometer for odour-sniffing tests, Jet Stream Olfactometer (JSO) for odour-blowing tests, and visual analogue scale (VAS). Evaluations were performed pre-operatively, and 1 month, 6 months, and 1-year post-laryngec tomy. RESULTS: Thirty-two patients were included in the study. The median recognition thresholds using the T&T and JSO were 1.4 and 2.2 before surgery, 5.8 and 5.4 at 1 month, 5.8 and 5.2 at 6 months, and 5.8 and 5.0 at 1 year after surgery, respectively. Results of the olfactory threshold test in both T&T and JSO and VAS score were significantly worse after surgery compared to that before laryngectomy (p < 0.05). The degree of increase was significantly smaller with JSO than with T&T (p < 0.05). CONCLUSION: While we could not prove normal olfaction in patients after laryngectomy, the odour-blowing test was superior to the odour-sniffing test in detecting patients with residual olfaction. Simply blowing a scent is insufficient to obtain good olfaction; active airflow is crucial for recognizing odours. PMID:35348858 | DOI:10.1007/s00405-022-07343-5 View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.