Head & NeckEffects of PPAR‐γ agonists on oral cancer cell lines: Potential horizons for chemopreventives and adjunctive therapiesAbstract Background Peroxisome proliferator‐activated receptor‐gamma (PPAR‐γ) activators have anti‐cancer effects. Our objective was to determine the effect of PPAR‐γ ligands 15‐deoxy‐D12,14‐Prostaglandin J2 (15‐PGJ2) and ciglitazone on proliferation, apoptosis, and NF‐κB in human oral squamous cell carcinoma cell lines. Methods NA and CA9‐22 cells were treated in...
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pubmed: sleep apneaImpact of Alcohol Consumption on Snoring and Sleep Apnea: A Systematic Review and Meta-analysis.Related ArticlesImpact of Alcohol Consumption on Snoring and Sleep Apnea: A Systematic Review and Meta-analysis. Otolaryngol Head Neck Surg. 2020 Jun 09;:194599820931087 Authors: Burgos-Sanchez C, Jones NN, Avillion M, Gibson SJ, Patel JA, Neighbors J, Zaghi S, Camacho M Abstract OBJECTIVE: To systematically review the international literature for studies evaluating the effect of alcohol...
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OncologyRadiotherapy treatment for lung cancer: Current status and future directions.Related ArticlesRadiotherapy treatment for lung cancer: Current status and future directions. Respirology. 2020 Jun 09;: Authors: Vinod SK, Hau E Abstract Radiotherapy is an important modality used for the treatment of lung cancer. Seventy-seven percent of all patients with lung cancer have an evidence-based indication for radiotherapy, although it is often underutilized. Radiotherapy can be used as curative or...
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Head and NeckCreation of a New Educational Podcast: "Headmirror's ENT in a Nutshell".Related ArticlesCreation of a New Educational Podcast: "Headmirror's ENT in a Nutshell". Otolaryngol Head Neck Surg. 2020 Jun 09;:194599820930662 Authors: Barnes JH, Choby G, Smith AJ, Kiessling P, Marinelli JP, Bowe S, Carlson ML Abstract Podcasts are online digital audio programs that are disseminated via online subscription that are easily accessible through computers or smartphones. Increasingly, residents and...
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bioRxiv Subject Collection: Evolutionary BiologyRecombination and purifying selection preserves covariant movements of mosaic SARS-CoV-2 protein S [NEW RESULTS]In depth evolutionary and structural analyses of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) isolated from bats, pangolins, and humans are necessary to assess the role of natural selection and recombination in the emergence of the current pandemic strain. The SARS-CoV-2 S glycoprotein unique features have been associated...
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OtorhinolaryngologyPercutaneous tracheostomy simulation training for ENT physicians in the treatment of COVID-19-positive patientsPublication date: Available online 10 June 2020Source: European Annals of Otorhinolaryngology, Head and Neck DiseasesAuthor(s): Valentin Favier, Antoine Kimmoun, Amélie Gatin, Patrice GalletOtorhinolaryngologyWed Jun 10, 2020 13:41Mark above section as read ScienceDirect Publication: Annales françaises d'Oto-rhino-laryngologie et de Pathologie Cervico-facialeImpact du...
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Journal of Craniofacial Surgery - Published Ahead-of-PrintGiant Mixed Tumor of the Skin Affecting the HemifaceMixed tumor of the skin (MTS) is a rare skin adnexal neoplasm occurring in sweat glands. It is usually benign, measures 0.5 to 3 cm, and presents as a slowly growing, painless, firm nodule commonly in the head and neck regions. Owing to its rarity and lack of distinctive clinical manifestations, confirmative diagnosis is made on the basis of its pathologic features. Malignant MTS also develops...
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Biomedicine & PharmacotherapySulfurous thermal waters stimulate the osteogenic differentiation of human mesenchymal stromal cells – An <em>in vitro</em> studyPublication date: September 2020Source: Biomedicine & Pharmacotherapy, Volume 129Author(s): Laura Gambari, Brunella Grigolo, Giuseppe Filardo, Francesco GrassiBiomedicine & PharmacotherapyWed Jun 10, 2020 14:12Peroxiredoxin-1 ameliorates pressure overload-induced cardiac hypertrophy and fibrosisPublication date: September...
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1Mol Cancer Ther. 2019 Oct;18(10):1852-1862. doi: 10.1158/1535-7163.MCT-18-0965. Epub 2019 Jul 18.Genomic Profiling of Blood-Derived Circulating Tumor DNA From Patients With Colorectal Cancer: Implications for Response and Resistance to Targeted TherapeuticsIn Sil Choi # 1 2, Shumei Kato # 3, Paul T Fanta 1, Lawrence Leichman 1, Ryosuke Okamura 1, Victoria M Raymond 4, Richard B Lanman 4, Scott M Lippman 1, Razelle Kurzrock 1Affiliations expandPMID: 31320401 DOI: 10.1158/1535-7163.MCT-18-0965Free...
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pubmed: "bmc med educ"[jour]Program on high value cost-conscious education in intensive care: Educational program on prediction of outcome and cost awareness on Intensive Care admission.Related ArticlesProgram on high value cost-conscious education in intensive care: Educational program on prediction of outcome and cost awareness on Intensive Care admission. BMC Med Educ. 2020 Jun 08;20(1):186 Authors: van Wagenberg L, Beurskens CJP, Stegeman I, Müller MCA Abstract BACKGROUND: Intensive Care (ICU)...
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Technologies in Treatment of Head & NeckExamination of a dose evaluation method for floor-mounted kV X-ray image-guided radiation therapy systems.Related ArticlesExamination of a dose evaluation method for floor-mounted kV X-ray image-guided radiation therapy systems. Radiol Phys Technol. 2020 Jun 08;: Authors: Hamada K, Fujibuchi T, Yoshida N, Ohura H Abstract Floor-mounted kV X-ray image-guided radiation therapy systems (such as ExacTrac) are used to treat tumors in movable body regions such...
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Rambam Maimonides Med JThe Ethics of Error in Medicine.Related ArticlesThe Ethics of Error in Medicine. Rambam Maimonides Med J. 2020 Jun 07;: Authors: Grossman SA, Gurley KL, Wolfe RE Abstract The practice of medicine forces medical practitioners to make difficult and challenging choices on a daily basis. On the one hand we are obligated to cure with every resource available, while on the other hand we put the patient at risk because our treatments are flawed. To understand the ethics of error...
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1Otolaryngol Head Neck Surg. 2020 Jun 9;194599820931804. doi: 10.1177/0194599820931804. Online ahead of print.Artificial Intelligence Applications in Otology: A State of the Art ReviewEunice You 1, Vincent Lin 2, Tamara Mijovic 3, Antoine Eskander 2, Matthew G Crowson 2Affiliations expandPMID: 32513061 DOI: 10.1177/0194599820931804AbstractObjective: Recent advances in artificial intelligence (AI) are driving innovative new health care solutions. We aim to review the state of the art of AI in otology...
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1Proc Natl Acad Sci U S A. 2020 Jun 8;202001270. doi: 10.1073/pnas.2001270117. Online ahead of print.GPCR-dependent Biasing of GIRK Channel Signaling Dynamics by RGS6 in Mouse Sinoatrial Nodal CellsAllison Anderson 1, Ikuo Masuho 2, Ezequiel Marron Fernandez de Velasco 1, Atsushi Nakano 3, Lutz Birnbaumer 4 5, Kirill A Martemyanov 2, Kevin Wickman 6Affiliations expandPMID: 32513692 DOI: 10.1073/pnas.2001270117AbstractHow G protein-coupled receptors (GPCRs) evoke specific biological outcomes while...
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Antimicrobial Resistance and Infection Control - Latest ArticlesChallenges regarding the control of environmental sources of contamination in healthcare settings in low-and middle-income countries - a narrative reviewHealthcare-associated infections (HAI) especially outbreaks of multi-drug-resistant organisms within hospitals are recognized as a major contributor to morbidity and mortality of hospitalized patients. The hea...Antimicrobial Resistance and Infection Control - Latest ArticlesTue Jun...
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American Journal of Neuroradiology current issueNeuroradiologists, Be Mindful of the Neuroinvasive Potential of COVID-19 [LETTERS]American Journal of Neuroradiology current issueWed Jun 10, 2020 17:59High Prevalence of Spinal Cord Cavernous Malformations in the Familial Cerebral Cavernous Malformations Type 1 Cohort [SPINE]BACKGROUND AND PURPOSE:Cavernous malformations occur most often in the brain but can occur in the spinal cord. Small studies of patients with familial cerebral cavernous malformations...
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Journal of AnatomySex‐specific ontogenetic patterns of cranial morphology, theoretical bite force, and underlying jaw musculature in fishers and American martensI examined sex‐specific ontogenetic changes in cranial morphology, musculature, and theoretical bite force in the fisher (Pekania pennanti ) and American marten (Martes americana ). I found that cranial shape development drives ontogenetic increases in relative bite force by broadening the zygomatic arches and enlargement of the sagittal...
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Stem Cells and DevelopmentEvaluating In Vitro Neonatal Hypoxic-Ischemic Injury Using Neural Progenitors Derived from Human Embryonic Stem CellsStem Cells and Development, Ahead of Print.Stem Cells and DevelopmentWed Jun 10, 2020 10:00Re: "Exosomes Derived from Bone Marrow Mesenchymal Stem Cells as Treatment for Severe COVID-19" by Sengupta et al.Stem Cells and Development, Ahead of Print.Stem Cells and DevelopmentWed Jun 10, 2020 10:00Response to Kim et al. re: "Exosomes Derived from Bone Marrow...
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Otolaryngology IndianSensitivity and Specificity of High-Resolution Computed Tomography (HRCT) of Temporal Bone in Diagnosing Cholesteatoma and Its Correlation with Intraoperative FindingsAbstract High resolution computed tomography (HRCT) of temporal bone helps in understanding the complex anatomy of temporal bone and in identifying disease in temporal bone. However, its role in diagnosing cholesteatoma and analyzing its extent and complications is not established unequivocally. Present study was...
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Otology & Neurotology - Featured Articles - Featured ArticlesCongenital External Auditory Canal Cholesteatoma Resected by a Transcanal Endoscopic ApproachObjective: To describe the first case of congenital external auditory canal cholesteatoma resected via a transcanal endoscopic approach and describe the possible pathologenesis of cholesteatoma. Patient: A 2-year-old female patient presented with a cholesteatoma that extended from the floor of the external auditory bony canal to the inferior...
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Looking beyond the fog—apomorphine demystifiedLK Prashanth, R Jayachandran, S Ragavendra, Rajesh B IyerAnnals of Indian Academy of Neurology 2020 23(3):363-364Annals of Indian Academy of Neurology : 2015 - 18(2)Wed Jun 10, 2020 00:00Opercular syndrome presenting as trismus: An interesting findingManeesh Shakywar, Kanchana Pillai, Rajesh Kumar Singh, Anuj Prabhakar, Deepa Dash, Rohit Bhatia, Manjari TripathiAnnals of Indian Academy of Neurology 2020 23(3):417-418Annals of Indian Academy of Neurology...
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CancerFirst-in-human study of the PARP/tankyrase inhibitor E7449 in patients with advanced solid tumours and evaluation of a novel drug-response predictorCancer01:25Mark above section as read Investigative Radiology - Current IssueQuantification of Avoidable Radiation Exposure in Interventional Fluoroscopy With Eye Tracking TechnologyObjectives Reducing avoidable radiation exposure during medical procedures is a top priority. The purpose of this study was to quantify, for the first time, the percentage...
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Case Reports in MedicineGiant Isolated Omphalocele: Role of Prenatal Diagnosis in Prognostic Asessment and Perinatal ManagementOmphalocele is a congenital malformation of the abdominal wall consisting of a protrusion of the abdominal contents at the base of the umbilical cord. It has a high association with genetic and structural defects; however, if the latter is ruled out, its prognosis improves significantly. Prenatal diagnosis has a key role in this condition as omphalocele can be diagnosed...
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Viruses, Vol. 12, Pages 627: Development and Application of Performance Assessment Criteria for Next-Generation Sequencing-Based HIV Drug Resistance AssaysViruses, Vol. 12, Pages 627: Development and Application of Performance Assessment Criteria for Next-Generation Sequencing-Based HIV Drug Resistance Assays Viruses doi: 10.3390/v12060627 Authors: Michael G. Becker Dun Liang Breanna Cooper Yan Le Tracy Taylor Emma R. Lee Sutan Wu Paul Sandstrom Hezhao Ji Next-generation sequencing (NGS)-based HIV...
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Nutrients, Vol. 12, Pages 1734: How Important Is Eating Rate in the Physiological Response to Food Intake, Control of Body Weight, and Glycemia?Nutrients, Vol. 12, Pages 1734: How Important Is Eating Rate in the Physiological Response to Food Intake, Control of Body Weight, and Glycemia? Nutrients doi: 10.3390/nu12061734 Authors: Georgia Argyrakopoulou Stamatia Simati George Dimitriadis Alexander Kokkinos The link between eating rate and energy intake has long been a matter of extensive research....
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Journal of ImagingJ. Imaging, Vol. 6, Pages 46: A Review on Computer Vision-Based Methods for Human Action RecognitionJ. Imaging, Vol. 6, Pages 46: A Review on Computer Vision-Based Methods for Human Action Recognition Journal of Imaging doi: 10.3390/jimaging6060046 Authors: Mahmoud Al-Faris John Chiverton David Ndzi Ahmed Isam Ahmed Human action recognition targets recognising different actions from a sequence of observations and different environmental conditions. A wide different applications...
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International Journal of Molecular SciencesIJMS, Vol. 21, Pages 4151: The Ubiquitin-Proteasome System Does Not Regulate the Degradation of Porcine β-Microseminoprotein during Sperm CapacitationIJMS, Vol. 21, Pages 4151: The Ubiquitin-Proteasome System Does Not Regulate the Degradation of Porcine β-Microseminoprotein during Sperm Capacitation International Journal of Molecular Sciences doi: 10.3390/ijms21114151 Authors: Lucie Tumova Michal Zigo Peter Sutovsky Marketa Sedmikova Pavla Postlerova Sperm...
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International Journal of Environmental Research and Public HealthIJERPH, Vol. 17, Pages 4152: Convolution-and Attention-Based Neural Network for Automated Sleep Stage ClassificationIJERPH, Vol. 17, Pages 4152: Convolution-and Attention-Based Neural Network for Automated Sleep Stage Classification International Journal of Environmental Research and Public Health doi: 10.3390/ijerph17114152 Authors: Zhu Luo Yu Analyzing polysomnography (PSG) is an effective method for evaluating sleep health; however,...
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Cancers, Vol. 12, Pages 1515: Normalized Pulmonary Artery Diameter Predicts Occurrence of Postpneumonectomy Respiratory Failure, ARDS, and MortalityCancers, Vol. 12, Pages 1515: Normalized Pulmonary Artery Diameter Predicts Occurrence of Postpneumonectomy Respiratory Failure, ARDS, and Mortality Cancers doi: 10.3390/cancers12061515 Authors: Elisa Daffrè Mathilde Prieto Haihua Huang Aurélie Janet-Vendroux Kim Blanc Yen-Lan N'Guyen Ludovic Fournel Marco Alifano Hypothesizing that pulmonary artery diameter...
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Antibiotics, Vol. 9, Pages 317: Synthesis and Anti-Saprolegnia Activity of New 2',4'-Dihydroxydihydrochalcone DerivativesAntibiotics, Vol. 9, Pages 317: Synthesis and Anti-Saprolegnia Activity of New 2',4'-Dihydroxydihydrochalcone Derivatives Antibiotics doi: 10.3390/antibiotics9060317 Authors: Enrique Werner Iván Montenegro Bastian Said Patricio Godoy Ximena Besoain Nelson Caro Alejandro Madrid In the present study, seven 2',4'-dihydroxydihydrochalcone derivatives (compounds 3–9) were synthesized...
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