Abstract
In this study, we performed Monte Carlo calculations to investigate photo-thermal effects on melanoma therapy. For this purpose, we simulated the light propagation in biological tissue. The propagation of laser light originates from a source point inside a single layer of light skin with a concentration of melanosomes \((f_{\text{mel}} = 3\% )\) . This single layer includes the epidermal with a thickness of 60 \(\upmu{\text{m}}.\) Various important wavelengths are applied for photo-thermal therapy (PTT), such as Alexandrite laser, Ruby laser, and Nd:YAG, respectively. Accordingly, a single layer of skin is exposed to laser. It is demonstrated that the exposure to laser is a suitable option at a wavelength of \(\lambda =\) 755 nm, which is useful to improve the therapeutic treatment compared to the lasers of wavelengths of \(\lambda =\) 694 nm and \(\lambda =\) 1064 nm, respectively. It is therefore possible to enhance the thermal treatment for light-skinned patients. The evaluation of temporal and spatial distributions is investigated versus the temperature, while the effects of relaxation time and thermal damage on the epidermal are involved.
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