Sortilin limits EGFR signaling by promoting its internalization in lung cancer

Sortilin limits EGFR signaling by promoting its internalization in lung cancer

Nature Communications, Published online: 30 October 2017; doi:10.1038/s41467-017-01172-5

Disruptions in epidermal growth factor receptor (EGFR) trafficking has been linked to tumor progression. Here the authors show that sortilin limits cell proliferation and tumor growth by promoting EGFR internalization.

from # All Medicine by Alexandros G. Sfakianakis via alkiviadis.1961 on Inoreader http://ift.tt/2lre75n