Alexandros G .Sfakianakis,ENT,Anapafeos 5 Agios Nikolaos Crete 72100 Greece,00302841026182

Τετάρτη 22 Απριλίου 2020

Medicine by Alexandros G. Sfakianakis,


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Null Cell Adenoma of the Pituitary: Pseudo-rosettes Say It Best When Immunohistochemistry Says Nothing At All!Related ArticlesNull Cell Adenoma of the Pituitary: Pseudo-rosettes Say It Best When Immunohistochemistry Says Nothing At All! Head Neck Pathol. 2019 Dec;13(4):677-680 Authors: Singh V, Gupta K, Salunke P, Dhandapani SS Abstract Null cell adenoma is composed of adenohypophyseal cells that show no evidence of any specific cell type differentiation by immunohistochemistry or transcription factors...
Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης
09:58
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Leukocyte-mimicking nanovesicles for effective doxorubicin delivery to treat breast cancer and melanoma.Related ArticlesLeukocyte-mimicking nanovesicles for effective doxorubicin delivery to treat breast cancer and melanoma. Biomater Sci. 2020 Jan 01;8(1):333-341 Authors: Molinaro R, Martinez JO, Zinger A, De Vita A, Storci G, Arrighetti N, De Rosa E, Hartman KA, Basu N, Taghipour N, Corbo C, Tasciotti E Abstract In the last decades, several approaches were developed to design drug delivery systems...
Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης
09:57
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A case of ruptured splenic cyst with elevated serum levels of CEA treated by laparoscopic unroofing.Related ArticlesA case of ruptured splenic cyst with elevated serum levels of CEA treated by laparoscopic unroofing. Clin J Gastroenterol. 2019 Dec;12(6):642-649 Authors: Okuno M, Yuasa N, Takeuchi E, Goto Y, Miyake H, Nagai H, Yoshioka Y, Miyata K Abstract Splenic cysts are rare and tend to have elevated tumor markers, of which carbohydrate antigen (CA) 19-9 is the most frequently elevated. Therefore,...
Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης
09:56
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Minimally invasive lateral approaches for the treatment of spinal tumors: single-position surgery without the "flip".Related ArticlesMinimally invasive lateral approaches for the treatment of spinal tumors: single-position surgery without the "flip". J Spine Surg. 2020 Mar;6(1):62-71 Authors: Laratta JL, Weegens R, Malone KT, Chou D, Smith WD Abstract Although primary tumors of the spine and neural elements are rare, metastatic disease to the spine is quite common. Traditionally, surgical treatment...
Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης
09:55
The Benefits of Adjuvant Trastuzumab for HER-2-Positive Salivary Gland Cancers.
The Benefits of Adjuvant Trastuzumab for HER-2-Positive Salivary Gland Cancers.: Related ArticlesThe Benefits of Adjuvant Trastuzumab for HER-2-Positive Salivary Gland Cancers.Oncologist. 2020 Apr 20;:Authors: Hanna GJ, Bae JE, Lorch JH, Haddad RI, Jo VY, Schoenfeld JD, Margalit DN, Tishler RB, Goguen LA, Annino DJ, Chau NGAbstract BACKGROUND: Although high-grade salivary gland cancers (SGCs) often express androgen receptor (AR) and/or HER-2/neu, therapeutically targeting these receptors...
Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης
09:49
Characteristics of Atypical Orbital Complications of Sinusitis. : Five patients were identified with atypical complications in the orbital area. Two of the 5 patients exhibited vision loss without any other symptoms. Two patients showed diplopia with or without ptosis. One patient had a headache and ptosis. Complete recovery was noted in 4 of the 5 patients after endoscopic sinus surgery.
Characteristics of Atypical Orbital Complications of Sinusitis.: Related ArticlesCharacteristics of Atypical Orbital Complications of Sinusitis.J Craniofac Surg. 2020 Apr 16;:Authors: Kim BY, Lee S, Jeon J, Lim IG, Choi GCAbstract INTRODUCTION: Orbital complications of rhinosinusitis in adults are scarcely discussed in the literature. We defined atypical orbital complications as those without typical orbital invasion and not classified by the Chandler classification. These complications...
Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης
09:49
Modified Endoscopic Dacryocystorhinostomy Using the Middle Uncinate Process Approach.
Modified Endoscopic Dacryocystorhinostomy Using the Middle Uncinate Process Approach.: Related ArticlesModified Endoscopic Dacryocystorhinostomy Using the Middle Uncinate Process Approach.J Craniofac Surg. 2020 Apr 16;:Authors: Yang J, Cao Z, Gu ZAbstract PURPOSE: Endoscopic dacryocystorhinostomy (EDCR) is advantageous in that it avoids facial scar formation, does not damage the medial canthus ligament, and recovers quickly. The main purpose of EDCR is to establish a fistula large enough...
Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης
09:48
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 Case Reports in MedicineGastrointestinal Cryptococcosis Associated with Intestinal LymphangiectasiaIntestinal lymphangiectasia is a pathological dilation of enteric lymphatic vessels resulting in lymph leakage to the intestinal lumen. This chronic lymph leakage leads to a state of immunosuppression secondary to the loss of humoral and cellular components of the immune system and represents a potential risk factor for opportunistic infections. We report a case of protein-losing enteropathy in a seemingly...
Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης
09:46
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 SAGE Publications Inc: Technology in Cancer Research & Treatment: Table of ContentsAtlas Sampling for Prone Breast Automatic Segmentation of Organs at Risk: The Importance of Patients' Body Mass Index and Breast Cup Size for an Optimized Contouring of the Heart and the Coronary VesselsTechnology in Cancer Research &Treatment, Volume 19, Issue , January-December 2020. Objective:Delineation of organs at risk is a time-consuming task. This study evaluates the benefits of using single-subject...
Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης
09:44
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 pubmed: sleepSerum levels of C1q/TNF-related protein-3 in inflammatory bowel disease patients and its inverse association with inflammatory cytokines and insulin resistance.Related ArticlesSerum levels of C1q/TNF-related protein-3 in inflammatory bowel disease patients and its inverse association with inflammatory cytokines and insulin resistance. IUBMB Life. 2020 Apr 20;: Authors: Mohamadinarab M, Ahmadi R, Gholamrezayi A, Rahvar F, Naghdalipour M, Setayesh L, Moradi N, Fadaei R, Chamani E, Tavakoli...
Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης
09:31
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 pubmed: philosophy for medic...Validity of the EQ-5D in patients with pemphigus vulgaris and pemphigus foliaceus.Related ArticlesValidity of the EQ-5D in patients with pemphigus vulgaris and pemphigus foliaceus. Br J Dermatol. 2019 04;180(4):802-809 Authors: Tamási B, Brodszky V, Péntek M, Gulácsi L, Hajdu K, Sárdy M, Szegedi A, Bata-Csörgő Z, Kinyó Á, Rencz F Abstract BACKGROUND: No studies to date have employed the EuroQoL EQ-5D questionnaire to assess health-related quality of life (HRQoL) in...
Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης
09:30
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 pubmed: "oral oncol"[jour]Continuing education in oral cancer during coronavirus disease 2019 (covid-19) outbreak.Related ArticlesContinuing education in oral cancer during coronavirus disease 2019 (covid-19) outbreak. Oral Oncol. 2020 Apr 16;:104713 Authors: da Cruz Perez DE, Passos KKM, Machado RA, Martelli-Junior H, Bonan PRF PMID: 32307326 [PubMed - as supplied by publisher]pubmed: "oral oncol"[jour]19hMark above section as read ScienceDirect Publication: International Journal of Biological...
Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης
09:29
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 Experimental Cell ResearchAlterations in osteocyte mediated osteoclastogenesis during estrogen deficiency and under ROCK-II inhibition: An <em>in vitro</em> study using a novel postmenopausal multicellular niche modelPublication date: Available online 21 April 2020Source: Experimental Cell ResearchAuthor(s): Irene Simfia, Jessica Schiavi, Laoise M. McNamaraExperimental Cell Research17hLong non-coding RNA HNF1A-AS1 upregulates OTX1 to enhance angiogenesis in colon cancer via the binding...
Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης
09:27
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 edoc: No conditions. Results ordered -Date Deposited.Long-Lived Particles at the Energy Frontier: The MATHUSLA Physics CaseWe examine the theoretical motivations for long-lived particle (LLP) signals at the LHC in a comprehensive survey of standard model (SM) extensions. LLPs are a common prediction of a wide range of theories that address unsolved fundamental mysteries such as naturalness, dark matter, baryogenesis and neutrino masses, and represent a natural and generic possibility for physics...
Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης
09:25
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 Proceedings of the National Academy of Sciences current issueGene drive and resilience through renewal with next generation Cleave and Rescue selfish genetic elements [Genetics]Gene drive-based strategies for modifying populations face the problem that genes encoding cargo and the drive mechanism are subject to separation, mutational inactivation, and loss of efficacy. Resilience, an ability to respond to these eventualities in ways that restore population modification with functional genes, is...
Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης
09:24
Predictors for Short-Term Efficacy of Allergen-Specific Sublingual Immunotherapy in Children with Allergic Rhinitis
Predictors for Short-Term Efficacy of Allergen-Specific Sublingual Immunotherapy in Children with Allergic Rhinitis: Background.A good compliance in allergen-specific sublingual immunotherapy (SLIT) often comes from good short-term efficacy. We aimed to evaluate the pretreatment parameters which can predict the short-term clinical efficacy in children that underwent SLIT. Methods. 517 children with allergic rhinitis (AR) that underwent SLIT were recruited in this study. Baseline clinical characteristics...
Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης
09:01
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 Hindawi Publishing CorporationMeasuring the Energy and Carbon Emission Efficiency of Regional Transportation Systems in China: Chance-Constrained DEA ModelsIn China, the transportation sector contributes about 18% of the total carbon emissions. This research contributes to measuring the energy and carbon emission efficiency (ECEE) of regional transportation systems (RTS) in China considering uncertain carbon emissions. A radial chance-constrained data envelopment analysis (DEA) model is developed...
Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης
09:01
Clinical Manifestations, Diagnosis, and Surgery of Inferior Oblique Muscle Ectopia
Clinical Manifestations, Diagnosis, and Surgery of Inferior Oblique Muscle Ectopia: Objectives. To summarize the clinical manifestations, diagnosis, treatment, and prognosis for inferior oblique muscle ectopia (IO-E). Subjects and Methods. Patients diagnosed with IO-E during strabismus surgery from March 2017 to September 2018 were included in this retrospective, cross-sectional study. All patients received preoperative Krimsky test, synoptophore, cycloplegia refraction, fundus torsion, and other...
Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης
09:00
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 Latest ResultsTargeting c-Met in triple negative breast cancer: preclinical studies using the c-Met inhibitor, Cpd ASummary Introduction Triple negative breast cancer (TNBC) represents a heterogeneous subtype of breast cancer that carries a poorer prognosis. There remains a need to identify novel drivers of TNBC, which may represent targets to treat the disease. c-Met overexpression is linked with decreased survival and is associated with the basal subtype of breast cancer. Cpd A, a kinase inhibitor...
Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης
08:46
Treating thyroid nodules by radiofrequency: is the delivered energy correlated with the volume reduction rate? A pilot study
Treating thyroid nodules by radiofrequency: is the delivered energy correlated with the volume reduction rate? A pilot study: AbstractObjectiveRadiofrequency ablation (RFA) was proven as effective in reducing thyroid nodules' volume. However, whether technical procedure aspects could influence the volume reduction rate (VRR) has not been clarified. This retrospective pilot study aimed to analyze the correlation of RFA power, duration, and energy with VRR.MethodsDuring the period from June to December...
Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης
08:45
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 Cancer Biotherapy & Radiopharmaceuticals - Table of Contents89Zr-Labeled Anti-PD-L1 Antibody Fragment for Evaluating In Vivo PD-L1 Levels in Melanoma Mouse ModelCancer Biotherapy and Radiopharmaceuticals, Ahead of Print.Cancer Biotherapy & Radiopharmaceuticals - Table of Contents1hLong Noncoding RNA HOTAIR Contributes to Progression in Hepatocellular Carcinoma by Sponging miR-217-5pCancer Biotherapy and Radiopharmaceuticals, Ahead of Print.Cancer Biotherapy & Radiopharmaceuticals - Table...
Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης
08:44
Efficacy and Safety of Galcanezumab for the Preventive Treatment of Migraine: A Narrative Review
Efficacy and Safety of Galcanezumab for the Preventive Treatment of Migraine: A Narrative Review: AbstractMigraine is a debilitating neurologic disease. People who experience migraine can have substantial disability, impaired functioning and a decreased quality of life (QoL). Expert recommendations suggest that people with frequent migraine attacks or severe impairment related to attacks may benefit from preventive treatment. Despite these recommendations and the existence of evidence-based guidelines...
Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης
08:43
Pharmacokinetics and Safety of Posaconazole Tablet Formulation in Chinese Participants at High Risk for Invasive Fungal Infection
Pharmacokinetics and Safety of Posaconazole Tablet Formulation in Chinese Participants at High Risk for Invasive Fungal Infection: AbstractIntroductionThis study characterized the multidose pharmacokinetic (PK) characteristics of posaconazole tablets used as prophylactic antifungal therapy in Chinese patients with acute myelogenous leukemia (AML) at risk for invasive fungal infection (IFI).MethodsParticipants in this open-label, single-arm, phase 1b study received posaconazole 300 mg twice daily...
Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης
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 CancerNetworkPhase III CheckMate-9ER Trial Meets Primary Endpoint in Advanced RCC TrialThe trial evaluated nivolumab in combination with cabozantinib compared to sunitinib in previously untreated advanced or metastatic renal cell carcinoma, meeting its primary endpoint of progression-free survival at final analysis. (Source: CancerNetwork)CancerNetwork9mILROG Recommends Alternative Radiation Treatment Schemes in Blood Cancer During COVID-19 PandemicThe International Lymphoma Radiation Oncology Group...
Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης
08:42
Medicine
S ScienceDirect Publication: European Annals of Otorhinolaryngology, Head and Neck DiseasesGuidelines of clinical practice for the management of swallowing disorders and recent dysphonia in the contexte of the COVID-19 pandemicPublication date: Available online 20 April 2020Source: European Annals of Otorhinolaryngology, Head and Neck DiseasesAuthor(s): A. Mattei, B Amy de la Bretèque, S. Crestani, L. Crevier-Buchman, C. Galant, S. Hans, A. Julien-Laferrière, A. Lagier, C. Lobryeau, F. Marmouset,...Medicine...
Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης
Tue Apr 21, 2020 09:04
Head and neck squamous cell cancer associated with lymphoproliferative malignancies is aggressive.
Head and neck squamous cell cancer associated with lymphoproliferative malignancies is aggressive.: Related ArticlesHead and neck squamous cell cancer associated with lymphoproliferative malignancies is aggressive.J Laryngol Otol. 2020 Apr 20;:1-3Authors: Li L, Hamilton L, Montgomery J, Stewart MAbstract BACKGROUND: Patients with non-Hodgkin's lymphoma and chronic lymphocytic leukaemia are at an elevated risk of further malignancy. Head and neck squamous cell carcinoma often presents with...
Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης
09:54
Potential of Pembrolizumab in Metastatic or Recurrent Head and Neck Cancer: Evidence to Date.
Potential of Pembrolizumab in Metastatic or Recurrent Head and Neck Cancer: Evidence to Date.: Related ArticlesPotential of Pembrolizumab in Metastatic or Recurrent Head and Neck Cancer: Evidence to Date.Onco Targets Ther. 2020;13:3047-3059Authors: McCusker MG, Orkoulas-Razis D, Mehra RAbstract Relapsed and/or metastatic head and neck squamous cell carcinoma (R/M HNSCC) is a heterogeneous disease previously associated with poor prognosis and limited treatment options until the advent and...
Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης
09:54
Chronic and Severe Non-Lichenoid Oral Ulcers Induced by Nivolumab - Diagnostic and Therapeutic Challenge: A Case Report.
Chronic and Severe Non-Lichenoid Oral Ulcers Induced by Nivolumab - Diagnostic and Therapeutic Challenge: A Case Report.: Related ArticlesChronic and Severe Non-Lichenoid Oral Ulcers Induced by Nivolumab - Diagnostic and Therapeutic Challenge: A Case Report.Case Rep Oncol. 2020 Jan-Apr;13(1):314-320Authors: Cardona AF, Ruiz-Patiño A, Ricaurte L, Zatarain-Barrón ZL, Barrón F, Arrieta OAbstract Due to the widespread use of immune checkpoint inhibitors and the growing research efforts in this...
Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης
09:54
The Carit Maneuver: A Novel Approach for the Relief of Shoulder Dystocia-A Case Series.
The Carit Maneuver: A Novel Approach for the Relief of Shoulder Dystocia-A Case Series.: https://www.researchgate.net/publication/340673646_The_Carit_Maneuver_A_Novel_Approach_for_the_Relief_of_Shoulder_Dystocia-A_Case_Series/fulltext/5e99732d4585150839e3ba09/The-Carit-Maneuver-A-Novel-Approach-for-the-Relief-of-Shoulder-Dystocia-A-Case-Series.pdfRelated ArticlesThe Carit Maneuver: A Novel Approach for the Relief of Shoulder Dystocia-A Case Series.AJP Rep. 2020 Apr;10(2):e133-e138Authors: Gei AF,...
Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης
09:53
Risk of head and neck cancer after chronic pancreatitis.
Risk of head and neck cancer after chronic pancreatitis.: Related ArticlesRisk of head and neck cancer after chronic pancreatitis.Ann Transl Med. 2020 Mar;8(5):213Authors: Chen CH, Chen CH, Lin CL, Hsu CY, Kao CHAbstractBackground: To evaluate the relation of head and neck cancer to chronic pancreatitis by analyzing Taiwan's National Health Insurance Research Database.Methods: We identified 11,237 patients with chronic pancreatitis as the case cohort, which was propensity score matched with another...
Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης
09:50
Comparison of Systemic EBV-positive T-Cell and NK-Cell Lymphoproliferative Diseases of Childhood Based on Classification Evolution: New Classification, Old Problems
Comparison of Systemic EBV-positive T-Cell and NK-Cell Lymphoproliferative Diseases of Childhood Based on Classification Evolution: New Classification, Old Problems: Systemic Epstein-Barr virus–positive T-cell and natural killer (NK)-cell lymphoproliferative diseases of childhood are a group of lethal diseases mostly affecting children and young adults. The Ohshima Grading System and the 2017 World Health Organization (WHO) classification have been used for classifying this spectrum, but these systems...
Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης
09:42
Pregnancy-associated Inflammatory Myofibroblastic Tumors of the Uterus Are Clinically Distinct and Highly Enriched for TIMP3-ALK and THBS1-ALK Fusions
Pregnancy-associated Inflammatory Myofibroblastic Tumors of the Uterus Are Clinically Distinct and Highly Enriched for TIMP3-ALK and THBS1-ALK Fusions: As inflammatory myofibroblastic tumors (IMTs) have become more widely recognized in the female genital tract, an intriguing subset of uterine tumors associated with pregnancy has emerged. Whether uterine IMTs occurring in the setting of pregnancy are clinically or biologically distinct from other uterine IMTs is unknown. Furthermore, little is known...
Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης
09:41
Primary Vascular Tumors of Bone: A Monoinstitutional Morphologic and Molecular Analysis of 427 Cases With Emphasis on Epithelioid Variants
Primary Vascular Tumors of Bone: A Monoinstitutional Morphologic and Molecular Analysis of 427 Cases With Emphasis on Epithelioid Variants: Recent molecular discoveries have refined vascular bone tumor classification. To investigate the clinical relevance of these refinements, we reviewed all cases of primary vascular bone tumors treated at our Institute. On the basis of morphology, cases were assessed immunohistochemically and molecularly. A total of 427 cases of primary vascular tumor of bone with...
Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης
09:41
Primary Cutaneous CD4+ Small/Medium T-Cell Lymphoproliferative Disorders: A Clinical, Pathologic, and Molecular Study of 60 Cases Presenting With a Single Lesion: A Multicenter Study of the French Cutaneous Lymphoma Study Group
Primary Cutaneous CD4+ Small/Medium T-Cell Lymphoproliferative Disorders: A Clinical, Pathologic, and Molecular Study of 60 Cases Presenting With a Single Lesion: A Multicenter Study of the French Cutaneous Lymphoma Study Group: Primary cutaneous CD4+ small/medium T-cell lymphoproliferative disorder (PCSMLPD) is a recently recognized entity in the 2017 World Health Organization (WHO) classification. It belongs to the T-follicular helper (TFH) lymphoproliferations. The clinical, pathologic, and molecular...
Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης
09:41
Follicular Thyroid Neoplasms: Comparison of Clinicopathologic and Molecular Features of Atypical Adenomas and Follicular Thyroid Carcinomas
Follicular Thyroid Neoplasms: Comparison of Clinicopathologic and Molecular Features of Atypical Adenomas and Follicular Thyroid Carcinomas: In follicular thyroid neoplasms without invasion, a diagnosis of atypical adenoma (AA) (follicular tumor of uncertain malignant potential) may be rendered if atypical features (indefinite capsular/vascular invasion, necrosis, solid growth, increased mitoses) are present. This study compares clinical, histologic, and molecular features of patients with AAs (n=31),...
Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης
09:41
Prostatic Metaplasia of the Vagina and Uterine Cervix: An Androgen-associated Glandular Lesion of Surface Squamous Epithelium
Prostatic Metaplasia of the Vagina and Uterine Cervix: An Androgen-associated Glandular Lesion of Surface Squamous Epithelium: Prostatic-type differentiation in the lower female genital tract is encountered rarely and its causes and clinical associations are not well established. Within the vagina, reports to date have invariably described ectopic prostatic-type differentiation as restricted to the lamina propria. We recently encountered a patient receiving testosterone for gender dysphoria whose...
Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης
09:40
A Modified Histopathologic Staging in Penile Squamous Cell Carcinoma Predicts Nodal Metastasis and Outcome Better Than the Current AJCC Staging
A Modified Histopathologic Staging in Penile Squamous Cell Carcinoma Predicts Nodal Metastasis and Outcome Better Than the Current AJCC Staging: Recently, the American Joint Committee on Cancer (AJCC) updated the staging system for penile squamous cell carcinoma. According to it, unlike its previous version, the involvement of urethra does not upstage the tumor; however, the involvement of corpora cavernosa (CC) does. The tumors involving CC are now staged pT3, whereas those involving corpora spongiosa...
Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης
09:40
Gastrointestinal Malakoplakia: Clinicopathologic Analysis of 26 Cases
Gastrointestinal Malakoplakia: Clinicopathologic Analysis of 26 Cases: Malakoplakia is an inflammatory process related to defective macrophage response to bacterial infection. To further characterize the clinicopathologic manifestations of gastrointestinal malakoplakia, 26 cases were identified from 6 institutions. Hematoxylin and eosin-stained slides and available stains were reviewed, and pertinent clinicopathologic features analyzed. Sixteen patients were women (62%). Mean patient age was 64 (range:...
Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης
09:40
Comparison of Systemic EBV-positive T-Cell and NK-Cell Lymphoproliferative Diseases of Childhood Based on Classification Evolution: New Classification, Old Problems
Comparison of Systemic EBV-positive T-Cell and NK-Cell Lymphoproliferative Diseases of Childhood Based on Classification Evolution: New Classification, Old Problems: Systemic Epstein-Barr virus–positive T-cell and natural killer (NK)-cell lymphoproliferative diseases of childhood are a group of lethal diseases mostly affecting children and young adults. The Ohshima Grading System and the 2017 World Health Organization (WHO) classification have been used for classifying this spectrum, but these systems...
Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης
09:39
Apocrine Variant of Pleomorphic Lobular Carcinoma In Situ: Further Clinical, Histopathologic, Immunohistochemical, and Molecular Characterization of an Emerging Entity
Apocrine Variant of Pleomorphic Lobular Carcinoma In Situ: Further Clinical, Histopathologic, Immunohistochemical, and Molecular Characterization of an Emerging Entity: To date, the apocrine variant of lobular carcinoma in situ (AP-LCIS) has been cursorily described as a subtype of lobular carcinoma in situ (LCIS). We retrospectively reviewed 34 cases of AP-LCIS (including 23 associated with invasive lobular carcinoma) to fully characterize it. AP-LCIS typically presented with screen-detected calcifications...
Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης
09:39
Skin-Colored Nodule on the Cutaneous Lip: Challenge
Skin-Colored Nodule on the Cutaneous Lip: Challenge:
Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης
09:38
A Fatal Infection With Subtle and Nonspecific Signs and Symptoms in a Neonate: Challenge
A Fatal Infection With Subtle and Nonspecific Signs and Symptoms in a Neonate: Challenge:
Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης
09:36
Brownish and Indurated Plaques With Yellowish Papules: Challenge
Brownish and Indurated Plaques With Yellowish Papules: Challenge: No abstract available
Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης
09:34
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 AUD : Last 20 articlesEffect of Noise Exposure on 1,382 Metallurgical Workers in Periodic Audiometric Evaluation: A Cohort StudyIntroduction: Noise-induced hearing loss is the most preventable cause of auditory impairment. Periodic audiometric evaluations are essential to monitor the hearing health of noise-exposed workers. Objective: To compare the evolution of audiometric thresholds in the initial three evaluations at frequencies of 3, 4, and 6 kHz in groups of workers exposed or not to noise....
Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης
09:33
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 pubmed: sleepInvestigation and diagnostic imaging of suspected pulmonary embolism during pregnancy and the puerperium: A review of the literature.Related ArticlesInvestigation and diagnostic imaging of suspected pulmonary embolism during pregnancy and the puerperium: A review of the literature. J Med Imaging Radiat Oncol. 2020 Apr 20;: Authors: Tester J, Hammerschlag G, Irving L, Pascoe D, Rees M Abstract Pulmonary embolism (PE) is a leading cause of maternal mortality with women at increased risk...
Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης
09:32
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 AA pubmed: head and neckOsteopromotive carbon dots promote bone regeneration through the PERK-eIF2α-ATF4 pathway.Related ArticlesOsteopromotive carbon dots promote bone regeneration through the PERK-eIF2α-ATF4 pathway. Biomater Sci. 2020 Apr 20;: Authors: Jin N, Jin N, Wang Z, Liu L, Meng L, Li D, Li X, Zhou D, Liu J, Bu W, Sun H, Yang B Abstract Bone defects are still an unsolved clinical issue that must be overcome. Carbon dots have shown very promising effects in biological therapy. In the current...
Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης
09:31
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 pubmed: philosophy for medic...Long-term outcomes after childhood convulsive status epilepticus.Related ArticlesLong-term outcomes after childhood convulsive status epilepticus. Curr Opin Pediatr. 2019 12;31(6):763-768 Authors: Pujar S, Scott RC Abstract PURPOSE OF REVIEW: It is widely accepted that childhood convulsive status epilepticus (CSE) has associated short-term and long-term mortality and morbidity. However, the role of CSE itself on subsequent adverse outcomes is still debated. In addition,...
Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης
09:29
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 ScienceDirect Publication: Cell ReportsBeta-Catenin Causes Adrenal Hyperplasia by Blocking Zonal TransdifferentiationPublication date: 21 April 2020Source: Cell Reports, Volume 31, Issue 3Author(s): Emanuele Pignatti, Sining Leng, Yixing Yuchi, Kleiton S. Borges, Nick A. Guagliardo, Manasvi S. Shah, Gerard Ruiz-Babot, Dulanjalee Kariyawasam, Makoto Mark Taketo, Ji Miao, Paula Q. Barrett, Diana L. Carlone, David T. BreaultScienceDirect Publication: Cell Reports18hProfiling of Small Ribosomal Subunits...
Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης
09:27
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 edoc: No conditions. Results ordered -Date Deposited.The ABC taxonomy for medication adherence translated into French and GermanWe translated the ABC adherence taxonomy (i.e., seven terms and their corresponding definitions) published by Vrijens et al. (2012) into French (F) and German (G) without changing the original meaning with the aim to promote a standardised taxonomy for medication adherence to French- and German-speaking researchers and clinicians.; A Delphi survey was performed. To generate...
Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης
09:26
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 Emergency Medicine Journal Online FirstPrognostic accuracy of the quick Sequential Organ Failure Assessment (qSOFA)-lactate criteria for mortality in adults with suspected bacterial infection in the emergency department of a hospital with limited resourcesBackgroundRoutine use of the Sequential Organ Failure Assessment (SOFA) score to prognosticate patients with sepsis is challenged by the requirement to perform numerous laboratory tests. The prognostic accuracy of the quick SOFA (qSOFA) without...
Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης
09:25
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 Proceedings of the National Academy of Sciences current issueReply to Nock and Nielsen: On the work of Nock and Nielsen and its relationship to the additive tree [Physical Sciences]The observation that decision trees are boosting algorithms, as cited in our work (1) and acknowledged by Nock and Nielsen (2), was first established by refs. 3 and 4. This was later used by refs. 5 and 6 to develop, to the best of our knowledge, the first decision tree...Proceedings of the National Academy of Sciences...
Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης
09:22
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 Clinical Oral InvestigationsThe efficacy of different cleaning protocols for the sealer-contaminated access cavityAbstract Objectives Sealer remnants in the access cavity may negatively affect coronal seal and cause tooth discoloration. This study sought to evaluate the efficacy of different cleaning protocols for the sealer-contaminated access cavity. Materials and methods Sixty extracted human molars were accessed, chemomechanically prepared and warm vertically obturated...Clinical Oral Investigations11hMark...
Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης
09:21
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 Journal of Plastic, Reconstructive & Aesthetic SurgeryA plastic surgery service response to COVID-19 in one of the largest teaching hospitals in EuropeCOVID-19 is presenting a colossal challenge to frontline NHS staff. This paper highlights how plastic surgery teams can use their diverse skills and resources in times of crisis. Through effective strategy and leadership we present how we are adapting as a department to serve our plastic surgery patients, other hospital teams and the Trust.Journal...
Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης
09:20
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 Planta MedicaIdentification and α-Glucosidase Inhibitory Activity of Meroterpenoids from Hericium erinaceusPlanta MedDOI: 10.1055/a-1146-8369 Hericium erinaceus is a very popular edible and medicinal mushroom used for the treatment of enervation and gastrointestinal diseases in Eastern Asia. Chemical investigation on the fruiting body of Hericium erinaceus led to the isolation of 4 new (1 – 4) and 10 known meroterpenoids (5 – 14). The structures of new compounds were determined via analysis of NMR...
Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης
09:18
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 Latest ResultsRadiolytic degradation of chlorobenzene in aerated and deoxygenated aqueous solutionsAbstract Radiation-induced degradation of chlorobenzene was conducted at 0.1, 0.4, 0.5, 0.7, and 1.0 mmol/dm3 concentrations in aerated environment and at 1.0 mmol/dm3 in oxygen-free and N2O-saturated solutions. The results demonstrated that the elimination of chloride is important when the solution is oxygen free, because the \( {\mathrm{e}}_{\mathrm{aq}}^{-} \) attacks at the ipso position of the...
Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης
09:16


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Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,00306932607174,alsfakia@gmail.com,
Telephone consultation 11855 int 1193,

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