Πέμπτη 17 Αυγούστου 2017

Network propagation: a universal amplifier of genetic associations

Nature Reviews Genetics 18, 551 (2017). doi:10.1038/nrg.2017.38

Authors: Lenore Cowen, Trey Ideker, Benjamin J. Raphael & Roded Sharan

Biological networks are powerful resources for the discovery of genes and genetic modules that drive disease. Fundamental to network analysis is the concept that genes underlying the same phenotype tend to interact; this principle can be used to combine and to amplify signals from individual



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