The aim of the study was to investigate the reliability and construct validity of the Polish adaptation of the Community Health Activities Model Program for Seniors (CHAMPS) physical activity questionnaire among the elderly. The sample included 104 volunteers, 75 women (age = 71.0 ± 5.0 years) and 29 men (age = 75.1 ± 6.6 years). To assess the reliability of the Polish version of the CHAMPS physical activity questionnaire, measurements were conducted by one-week test-retest. The construct validity...
09:05
Natural enzyme mimics have attracted considerable attention due to leakage of enzymes and their easy denaturation during their storage and immobilization procedure. Here in this study, for the first time, a new iron oxide hydroxide, ferrihydrite – Fe1.44O0.32 (OH) 3.68 magnetic nanoparticles were synthesized by bacterial strain named Comamonas testosteroni. The characterization of the produced magnetic nanoparticles was confirmed by transmission electron microscopy (TEM), Fourier-transform spectroscopy...
09:05
Retrolaminar block (RLB) and erector spinae plane block (ESPB) are alternative approaches to paravertebral block (PVB) and are advantageous in that they are easier and safer techniques compared with the traditional PVB. Many clinical reports of these blocks have described their efficacy for ipsilateral thoracic analgesia. The local anesthetic injection points of RLB and ESPB are the lamina and transverse process, respectively. Despite the similarity of the puncture sites, there have been no clinical...
02:05
Dementia directly influences the quality of life of a person suffering from this chronic illness. The caregivers or carers of dementia people provide critical support to them but are subject to negative health outcomes because of burden and stress. The intervention of mobile health (mHealth) has become a fast-growing assistive technology (AT) in therapeutic treatment of individuals with chronic illness. The purpose of this comprehensive study is to identify, appraise, and synthesize the existing...
Wed Mar 27, 2019 17:05
Soilborne pathogens affect plant growth and food production worldwide. The application of chemical fertilizers and pesticides to control plant diseases has harmful effects; fortunately, plant growth-promoting rhizobacteria can be used as a potential alternative strategy. Here, Paenibacillus jamilae HS-26 was selected for its highly antagonistic activity against several soilborne pathogens. The bacterium synthesized hydrolytic enzymes and released extracellular antifungal metabolites and volatile...
Wed Mar 27, 2019 15:05
Background. General anesthesia combining with a caudal block (CB) has been commonly performed in pediatric patients undergoing circumcision surgeries. However, some severe complications have been suspected of a caudal block in the combined use. To avoid these issues of a caudal block, this study introduces a novel dorsal penile nerve block (DPNB) via perineum guided by ultrasound as an alternative to a caudal block in pediatric circumcision surgeries. Methods. A total of 104 pediatric patients scheduled...
Wed Mar 27, 2019 14:05
Role of MMP-2(-1306 C/T) and TIMP-2(-418G/C) Polymorphism in Chinese Han Patients with Acne Vulgaris
Acne is the most common chronic inflammatory skin diseases. Multiple factors, such as hormonal, environmental, immunological, and genetic factors, are thought to be involved in acne. However, genetic studies have yet to elucidate the full mechanism of acne. The aim of this study was to investigate the association of MMP-2 (-1306C/T) and TIMP-2 (-418G/C) polymorphisms with the risk of acne vulgaris in a Chinese Han population. We also analyzed the correlation of clinical parameters and family history...
Wed Mar 27, 2019 14:05
Objective. To investigate the prevalence of infections due to carbapenem-resistant Klebsiella pneumoniae (CRKP) among ICU admission patients in central China and develop a reliable prediction model. Methods. Five hundred and seven consecutive ICU admission patients with Klebsiella pneumoniae (KP) infection were enrolled in this retrospective multicenter case-control study from January 2014 to June 2018. The prevalence and antimicrobial susceptibility pattern were analyzed. Multivariate analysis was...
Wed Mar 27, 2019 14:05
With gastrointestinal tract as the origin, gastrointestinal stromal tumor (GIST) is recognized as the very widespread mesenchymal tumor. A precise prognostic model of survival is required to guide the treatment options of patients with GIST. This study was designed to map the overall survival (OS) and cancer-specific survival (CSS) of GIST patients. According to the Surveillance, Epidemiology, and End Results (SEER) program database, we acquired the data of 6,713 patients with GIST who were diagnosed...
Wed Mar 27, 2019 14:05
Purpose. Anterior knee pain (AKP) is a common complication after tibia intramedullary nailing surgery, but yet the etiology is not fully revealed. Our study had two hypotheses. The first one is "after tibia intramedullary nailing with transtendinous approach, thigh muscles strength decreases and this loss of muscle strength causes AKP." Secondly, "lower extremity rotational profile is affected after tibia intramedullary nailing." Methods. Our study was planned retrospectively and included 40 patients,...
Wed Mar 27, 2019 13:05
Background. Repeated or continuous chronic psychological stress may induce diverse neuropsychiatric disorders; however, the underlying mechanisms remain unclear. In this study, we explored the expression profiles of long noncoding RNAs (lncRNAs) and mRNAs, along with their biological function and regulatory network, in mice after repeated social defeat (RSD) stress to explore their potential involvement in the development of anxiety-like behaviors. Main Methods. RNA-sequencing was used to screen...
Wed Mar 27, 2019 13:05
Lentiviral vectors have been used for gene therapy in the clinical phase in recent years. These vectors provide a tool for gene insertion, deletion, or modification in organisms. The K562 human cell line has been used extensively in hematopoietic research. Despite its broad application, it is hard-to-transfection and transduction. So, this study presents a simple method to increase the transduction efficiency of K562 cells with a low multiplicity of infection (MOI) of the virus particle. For this...
Wed Mar 27, 2019 12:05
The aims of the present work were to isolate and characterize fungal endophytic communities associated with healthy wheat (Triticum aestivum L.) plants, collected from the North China. Segregated endophytes were screened for their PGP traits, abiotic stresses (heavy metals, salinity, drought, and temperature), and antibiotic sensitivity. A total of 16 endophytic fungi were isolated using the culture-dependent approach from different tissue parts of wheat plants. Based upon their internal transcribed...
Wed Mar 27, 2019 11:05
Purpose. Reactive oxygen species (ROS)-induced cytotoxicity is an important mechanism by which cisplatin kills tumor cells. Glutathione peroxidase family (GPXs) is an important member of antioxidant system which metabolizes intracellular ROS and maintains homeostasis of cells. Altered expressions of GPXs enzymes, especially GPX1, have been described in a variety of human cancers. However, their functional roles in cisplatin-based chemoresistance in human malignancies including non-small cell lung...
Wed Mar 27, 2019 11:05
Urinary tract infection (UTI) and preeclampsia are common among pregnant women and are associated with adverse maternal-fetal and neonatal outcomes. Despite this, limited information exists on the association between UTIs and preeclampsia in Tanzania to guide specific management and thereby averting the adverse outcomes. A 1:2 matched case-control study (by age and gravidity) involving 131 pregnant women with preeclampsia (cases) and 262 without preeclampsia (controls) was conducted. Sociodemographic...
Wed Mar 27, 2019 10:05
AbstractThe transversal screw was introduced in order to overcome some disadvantages of the transocclusal screw. However, its mechanical risk has not been studied sufficiently. The main purpose of this research was to assess and compare stress distribution in the screws and abutment of a single‐crown implant with transversal and transocclusal screw models. Two 3‐D models were assembled to analyze a single implant‐supported prosthesis with transversal and transocclusal screws embedded in the...
Wed Mar 27, 2019 12:32
AbstractFlow‐energetics have been proposed as early indicators of progressive left ventricular (LV) functional impairment in patients with myocardial infarction (MI), but its correlation with individual MI parameters has not been fully explored. Using electro‐fluid‐structure interaction LV models, this study investigated the correlation between four MI parameters: infarct size, infarct multiplicity, regional enhancement of contractility at the viable myocardium area (RECVM) and left ventricular...
Mon Mar 25, 2019 17:54
AbstractIntroductionModeling the flow dynamics in cerebral aneurysms after the implantation of intra‐saccular devices is important for understanding the relationship between flow conditions created immediately post‐treatment and the subsequent outcomes. This information, ideally available a priori based on computational modeling prior to implantation, is valuable to identify which aneurysms will occlude immediately and which aneurysms will likely remain patent and would benefit from a different...
Wed Mar 20, 2019 10:25
SummaryThe membrane or interfacial viscosity is an important property in many multiphase and biofluidic situations, such as the red blood cell dynamics and emulsion stability. The immersed boundary method (IBM), which incorporates the dynamic flow‐membrane interaction via force distribution and velocity interpolation, has been extensively employed in simulations of such systems. Unfortunately, direct implementation of membrane viscosity in IBM suffers severe numerical instability, which causes...
Mon Mar 18, 2019 20:27
Abstract[1] This study aims to enhance the understanding of the relationship between Ilizarov fixator configuration and its effects on bone fracture healing. Using Taylor spatial frame (TSF) as an example, the roles of critical parameters (i.e. TSF ring diameter, wire pretension, fracture gap size and axial load) that govern fracture healing during the early stages were investigated by using computational modelling in conjunction with mechanical testing involving an advanced 3D optical measurement...
Thu Mar 14, 2019 11:54
Eko, a company that makes advanced and innovative stethoscopes that we really like, is now releasing its Eko DUO combination stethoscope/ECG device. The Eko DUO works along with a paired smartphone or tablet, allowing a physician to simultaneously record heart sounds and ECG (single lead) tracings at the point of care. The DUO makes it easy to capture ECG intervals and systolic time intervals that can help to diagnose heart failure and detect atrial fibrillation. All the data the device captures...
Wed Mar 27, 2019 20:45
Researchers at the University of British Columbia (UBC) have developed a nanocomposite biomaterial heart valve that could provide an alternative to the animal valves that are currently used as heart valve replacements. Moreover, the nanocomposite valves can be delivered to the heart through a transcatheter, allowing for minimally invasive placement. The new valve is aimed at high-risk patients. "Existing transcatheter heart valves are made of animal tissues, most often the pericardium membrane...
Wed Mar 27, 2019 19:56
Contraceptives are very effective, as long as they're administered on a tight schedule. All too often many women forget or ignore to take the pill, leading to unwanted surprises. Researchers at Georgia Tech, taking into account today's fashion of wearing unusual jewelry, have developed an earring, necklace, ring, and a wrist watch, each integrating a transdermal patch containing the hormone levonorgestrel. The jewelry releases the hormone at a steady rate (1.7 μg/cm2·h), at least when tested on...
Wed Mar 27, 2019 19:37
HemoSonics, based in Charlottesville, Virginia, won FDA de novo approval for its Quantra QPlus System and accompanying QPlus cartridge for point-of-care coagulation analysis. The system provides easy and rapid coagulation status, requiring only about a minute of labor from clinicians for each test. Initial results are available in about five minutes and the rest within about fifteen minutes. The system uses a sealed, disposable cartridge inside of which a panel of viscoelastic blood coagulation...
Wed Mar 27, 2019 19:28
The neurotransmitter glutamate seems to play an important part in a number of psychophysiologic processes. Migraines after spinal cord injuries, for example, are common typically due to a release of high concentrations of glutamate. Parkinson's and Alzheimer's diseases also tend to show higher glutamate levels in patients. Tracking the levels of this chemical is very difficult, and so the development of new therapies that moderate the release of glutamate is impeded. Now researchers at Purdue...
Wed Mar 27, 2019 18:59
Ablation of cardiac tissue is one of the most common ways of treating atrial fibrillation. Interventional cardiologists have to work quite a bit to make sure the energy they're delivering hits the correct areas. The HeartLight X3 System from CardioFocus is designed to make this process much faster and it has just been approved in the EU. Cardiac ablations generally involve performing pulmonary vein isolations, which can take over an hour to perform. By using the HeartLight X3, physicians are...
Wed Mar 27, 2019 18:34
A new species of mastodon from the Pleistocene of western North America, Mammut pacificus sp. nov. is herein recognized, with specimens identified throughout California and from two localities in southern Idaho. This new taxon differs from the contemporaneous M. americanum in having narrower teeth, most prominently in M3/m3, as well as six sacral vertebrae, femur with a proportionally greater mid-shaft diameter, and no mandibular tusks at any growth stage. All known Pleistocene Mammut remains from...
Wed Mar 27, 2019 02:00
Botryococcus braunii (Chlorophyta) is a green microalga known for producing hydrocarbons and exopolysaccharides (EPS). Improving the biomass productivity of B. braunii and hence, the productivity of the hydrocarbons and of the EPS, will make B. braunii more attractive for industries. Microalgae usually cohabit with bacteria which leads to the formation of species-specific communities with environmental and biological advantages. Bacteria have been found and identified with a few B. braunii strains,...
Wed Mar 27, 2019 02:00
Background The contemporary Italian wolf (Canis lupus italicus) represents a case of morphological and genetic uniqueness. Today, Italian wolves are also the only documented population to fall exclusively within the mitochondrial haplogroup 2, which was the most diffused across Eurasian and North American wolves during the Late Pleistocene. However, the dynamics leading to such distinctiveness are still debated. Methods In order to shed light on the ancient genetic variability of this...
Wed Mar 27, 2019 02:00
Background This study was designed to investigate the clinicopathological characteristics, treatment and survival of patients with pulmonary large cell neuroendocrine carcinoma (LCNEC). Methods The Surveillance, Epidemiology and End Results database was utilized to identify patients diagnosed with pulmonary LCNEC between 2004 and 2013. Kaplan–Meier analysis was conducted to determine the overall survival (OS) and cancer-specific survival (CSS) rate. Univariate survival analysis along...
Wed Mar 27, 2019 02:00
One of the greatest stressors for dogs living in animal shelters is social isolation. Many studies have demonstrated that human interaction reduces cortisol in shelter dogs, with the possibility that longer periods of interaction may yield greater effects. These types of interventions are contingent upon removing the dog from the kennel and any such reductions in cortisol are often lost when the dog returns to the kennel. More recently, animal shelters are utilizing short-term fostering programs...
Wed Mar 27, 2019 02:00
Background In biology, high-throughput experimental technologies, also referred as "omics" technologies, are increasingly used in research laboratories. Several thousands of gene expression measurements can be obtained in a single experiment. Researchers are routinely facing the challenge to annotate, store, explore and mine all the biological information they have at their disposal. We present here the Pixel web application (Pixel Web App), an original content management platform...
Wed Mar 27, 2019 02:00
Publication date: Available online 26 March 2019Source: International Journal of Radiation Oncology*Biology*PhysicsAuthor(s): Myong Kim, Jong Keun Kim, Jaehoon Lee, Young Seok Kim, Jae Lyun Lee, Cheol Kwak, Chang Wook Jeong, Seok-Soo Byun, Sang Cheol Lee, Chikara Ohyama, Youichi Arai, Hanjong AhnAbstractPurposeWe assessed the efficacy of adjuvant treatments in patients with peripelvic/ periureteral fat-infiltrating (pT3b), non-metastatic upper tract urothelial carcinoma (UTUC) treated with radical...
Wed Mar 27, 2019 12:49
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