BMJ, Online First,Reducing door-to-needle times in stroke thrombolysis to 13 min through protocol revision and simulation training: a quality improvement project in a Norwegian stroke centreBackgroundIn eligible patients with acute ischaemic stroke, rapid revascularisation is crucial for good outcome. At our treatment centre, we had achieved and sustained a median door-to-needle time of under 30 min. We hypothesised that further improvement could be achieved through implementing a revised treatment...
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Latest headlines from BMJ,Doctors' pensions: no trust in this governmentMahase reports that doctors will be able to halve pension contributions to ease tax burden.1 I won't hold my breath. A consultation will start at the end of June. Meanwhile, many doctors are worried...Latest headlines from BMJFri Jun 28, 2019 18:36NHS to change GP registration rules in response to growth of digital providersDigital first GP providers such as Babylon's GP at Hand should have to establish a physical location and...
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BMJ Current issue,A focused mapping review and synthesis of a priori risk factors associated with medical misconductBackgroundMedical misconduct is an international problem. It is judged according to whether a doctor has endangered the health of the public. Little is known about the risk factors associated with medical misconduct. To inform patient safety, we undertook a focused mapping review and synthesis (FMRS) of tribunal reports retrieved from the Medical Practitioners Tribunal Service (MPTS)....
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BMJ Open Current Issue,Research priorities in regional anaesthesia education and training: an international Delphi consensus surveyObjectivesEducation in regional anaesthesia covers several complex and diverse areas, from theoretical aspects to procedural skills, professional behaviours, simulation, curriculum design and assessment. The objectives of this study were to summarise these topics and to prioritise these topics in order of research importance. DesignElectronic structured Delphi questionnaire...
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BMJ Case Reports Last 6 Issues,Ischaemic stroke as the initial manifestation of systemic amyloidosisA previously healthy 54-year-old woman was admitted to the stroke unit with an acute ischaemic stroke attributed to atrial fibrillation newly diagnosed at the emergency room. Nevertheless, preliminary investigation on stroke aetiology revealed incidental hypoalbuminaemia in the context of nephrotic syndrome, while clinically, the patient developed progressive signs of cardiac failure raising the suspicion...
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BMC Research Notes,Gait screening of a population of young, healthy athletes by means of a portable, low-cost device unveils hidden left–right asymmetries in both quadriceps and anterior cruciate ligament forcesThe present study reports the on-field screening of a population of young soccer players in the pursuit of alterations in gait using a portable and low-cost gait analysis system composed of a Wii Balance Board...BMC Research NotesFri Jun 28, 2019 03:00Low dietary diversity and its influencing...
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International Journal of Radiation Oncology*Biology*Physics,Determining the "Organ-at-Risk" for Lymphedema Following Regional Nodal Irradiation in Breast CancerPublication date: Available online 28 June 2019Source: International Journal of Radiation Oncology*Biology*PhysicsAuthor(s): Jeffrey P. Gross, Connor M. Lynch, Anne Marie Flores, Sumanas W. Jordan, Irene B. Helenowski, Mahesh Gopalakrishnan, Dan Cutright, Eric D. Donnelly, Jonathan B. StraussAbstractPurposeLymphedema following regional nodal...
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Medical Image Analysis,Hierarchical Spherical Deformation for Cortical Surface RegistrationPublication date: Available online 29 June 2019Source: Medical Image AnalysisAuthor(s): Ilwoo Lyu, Hakmook Kang, Neil D. Woodward, Martin A. Styner, Bennett A. LandmanAbstractWe present hierarchical spherical deformation for a group-wise shape correspondence to address template selection bias and to minimize registration distortion. In this work, we aim at a continuous and smooth deformation field to guide...
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Medgadget,Protein-Loaded Antimicrobial Hydrogel to Treat, Prevent Bone InfectionsBone infections are quite common following orthopedic surgery or as a result of injury or disease. They can be incredibly difficult to treat, and heavy duty antibiotic regimens coupled with debridement surgery is the current approach. Even after all that, inflammation is a frequent side effect. Now, researchers at Georgia Tech have created a hydrogel material that can be used to treat bone infections and even prevent...
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Clinical Chemistry and Laboratory Medicine (CCLM), Correlations between serum and CSF pNfH levels...
Clinical Chemistry and Laboratory Medicine (CCLM),Correlations between serum and CSF pNfH levels in ALS, FTD and controls: a comparison of three analytical approachesJournal Name: Clinical Chemistry and Laboratory Medicine (CCLM)Issue: Ahead of printClinical Chemistry and Laboratory Medicine (CCLM)Fri Jun 28, 2019 15:56Mark above section as read Royal Society of Chemistry (Great Britain) Society for Analytical Chemistry Society of Public Analysts (Great Britain)Colorimetric detection of Ba2+, Cd2+...
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Antioxidants,Antioxidants, Vol. 8, Pages 202: Dietary Flavonoids for Immunoregulation and Cancer: Food Design for Targeting DiseaseAntioxidants, Vol. 8, Pages 202: Dietary Flavonoids for Immunoregulation and Cancer: Food Design for Targeting Disease Antioxidants doi: 10.3390/antiox8070202 Authors: Ahn-Jarvis Parihar Doseff Flavonoids, one of the most abundant phytochemicals in a diet rich in fruits and vegetables, have been recognized as possessing anti-proliferative, antioxidant, anti-inflammatory,...
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Allergology International,A case of anaphylaxis due to fish collagen in a gummy candyPublication date: Available online 28 June 2019Source: Allergology InternationalAuthor(s): Namiko Abe, Tomonobu Ito, Tomoko Kobayashi, Chizu Egusa, Tatsuo Maeda, Yukari Okubo, Ryoji TsuboiAllergology InternationalSat Jun 29, 2019 18:04γδ T cells enhance TSLP production and ILC2 accumulation in house dust mite-induced allergic airway inflammationPublication date: Available online 28 June 2019Source: Allergology InternationalAuthor(s):...
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Annals of Diagnostic Pathology,BK virus histopathologic disease severity does not predict allograft outcome in renal transplant recipientsPublication date: Available online 27 June 2019Source: Annals of Diagnostic PathologyAuthor(s): M. Lee Sanders, Melissa Swee, Mony Fraer, Sarat Kuppachi, Patrick Ten Eyck, Prerna RastogiAbstractAimsBK polyomavirus nephropathy (BKPyVN) is an important cause of allograft failure after renal transplantation. Despite early screening for the virus, allograft loss from...
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AnaesthesiaFood, fads, allergies and anaphylaxis with propofolAnaesthesiaFri Jun 28, 2019 19:38Mark above section as read BMC Anesthesiology - Latest ArticlesContinuous Adductor Canal Block used for postoperative pain relief after medial Unicondylar Knee Arthroplasty: a randomized, double-blind, placebo-controlled trialPeripheral nerve block and local infiltration analgesia (LIA) provide good analgesia after knee replacement. This study evaluated the additional analgesic efficacy of continuous adductor...
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Journal of Plastic, Reconstructive & Aesthetic SurgeryPreserved Nipple Erectile Function after Free Nipple Areolar Complex TransplantationIt is generally believed that sensory innervation and preservation of nipple erectile function are lost after free nipple areolar complex (NAC) transplantation. We, however, would like to present a case that already reported 'restored' nipple erectile function two weeks after free NAC transplantation following bilateral mastectomy and breast free flap reconstruction...
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The feeling of grip: novelty, error dynamics, and the predictive brainAbstractAccording to the free energy principle biological agents resist a tendency to disorder in their interactions with a dynamically changing environment by keeping themselves in sensory and physiological states that are expected given their embodiment and the niche they inhabit (Friston in Nat Rev Neurosci 11(2):127–138, 2010. doi:10.1038/nrn2787). Why would a biological agent that aims at minimising uncertainty in its encounters...
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Inflammation and type 2 diabetes: from basic science to treatmentTreatment of type 2 diabetes by targeting interleukin-1: a meta-analysis of 2921 patientsAbstractWith obesity and type 2 diabetes prevalence steadily increasing and no effective means in sight to support the population in obtaining and maintaining stable weight loss, there is an imminent need for pharmacological therapy to treat and prevent type 2 diabetes. Current anti-diabetic treatment is symptomatic, and very few drugs have both...
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Clinical impact of sarcopenia and dynapenia on diabetesAbstractSarcopenia as a progressive and generalized skeletal muscle disorder that is associated with an increased likelihood of adverse outcomes, including falls, fractures, physical disability, and mortality. On the other hand, an age-related decline in muscle strength prior to the reduction of muscle mass, is proposed to be "dynapenia". Sarcopenia and dynapenia have recently been recognized as a diabetic complications in type 2 diabetes. We...
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Tamarixetin protects against cardiac hypertrophy via inhibiting NFAT and AKT pathwayAbstractCardiac hypertrophy is a compensatory response in reaction to mechanical load that reduces wall stress by increasing wall thickness. Chronic hypertrophic remodeling involves cardiac dysfunction that will lead to heart failure and ultimately death. Studies have been carried out on cardiac hypertrophy for years, whereas the mechanisms have not been well defined. Tamarixetin (TAM), a natural flavonoid derivative...
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Problems with Compensation: Gleeson on Marilyn McCord Adams on EvilAbstractAccording to the most recent articulation of her view, Marilyn Adams's reply to the problem of horrendous evils states that God offers compensation to those who experience horrendous evils. This compensation includes the good of the incarnation of God and the good of identification with God in virtue of suffering horrendous evils. Andrew Gleeson has raised a series of objections to Adams's recent articulation. I argue that...
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Die Rubrik „Im Fokus"Tiefe Hirnstimulation des Kleinhirns reduziert die Ataxie bei der shaker -RatteVorsicht bei der Vernichtung von PatientenunterlagenIntrathekale Nusinersentherapie bei Erwachsenen mit spinaler MuskelatrophieAkinetisch-rigide Bewegungsstörungen unter AntikonvulsivaMagazinNeuromyelitis-optica-Spektrum-ErkrankungFacharzt für NeurologieErster epileptischer AnfallZusammenfassungZiel der Diagnostik nach einem ersten Anfallsereignis ist zunächst die ätiologische Einordnung, ob ein epileptischer...
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Correction to: Improved Singleton bound on frequency hopping sequences and optimal constructionsThe original version of this article unfortunately contained a mistake in an equation.Polynomial time bounded distance decoding near Minkowski's bound in discrete logarithm latticesAbstractWe propose a concrete family of dense lattices of arbitrary dimension n in which the lattice bounded distance decoding (BDD) problem can be solved in deterministic polynomial time. This construction is directly adapted...
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Spatial prediction of landslide susceptibility in Taleghan basin, IranAbstractIdentifying landslide-susceptible zones is warranted to prevent and mitigate associated hazards in mountainous regions, where a landslide is a destructive type of erosion. A landslide susceptibility map was developed for the Taleghan basin based on frequency ratio (FR), logistic regression (LR), maximum entropy (MaxEnt), and support vector machine (SVM) with radial base (RBF), sigmoid (SIG), linear (LN), and polynomial...
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Nicotinamide adenine dinucleotide emerges as a therapeutic target in aging and ischemic conditionsAbstractNicotinamide adenine dinucleotide (NAD+) has been described as central coenzyme of redox reactions and is a key regulator of stress resistance and longevity. Aging is a multifactorial and irreversible process that is characterized by a gradual diminution in physiological functions in an organism over time, leading to development of age-associated pathologies and eventually increasing the probability...
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Serological screening for coeliac disease in patients with juvenile idiopathic arthritisPublication date: Available online 7 June 2019Source: Arab Journal of GastroenterologyAuthor(s): Yasin Sahin, Sezgin Sahin, Kenan Barut, Fugen Cullu Cokugras, Tulay Erkan, Amra Adrovic, Tufan Kutlu, Ozgur KasapcopurAbstractBackground and study aimsJuvenile idiopathic arthritis (JIA) is characterized by autoimmune aetiology. A gene locus 4q27 related to rheumatoid arthritis, psoriatic arthritis, and coeliac disease...
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The Knowledge, Attitude, and Self-Reported Behaviors of Oncology Physicians Regarding Fertility Preservation in Adult Cancer PatientsAbstractThere is a growing concern about the fertility preservation for adult cancer patients of reproductive age. Very little literature exists about fertility preservation of cancer survivors in Chinese text. This study is first to describe the knowledge level, attitude, and practice behaviors among physicians concerning fertility preservation in adult cancer patients...
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Ιατρικά Άρθρα Medicine by Alexandros G. Sfakianakis,ENT PhD,Anapafseos 5 Agios Nikolaos 72100,Crete Greece,00302841026182,00306932607174,alsfakia@gmail.com
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