July-December 2019Volume 7 | Issue 2Page Nos. 139-322Online since Monday, December 16, 2019Accessed 802 times.PDF access policyJournal allows immediate open access to content in HTML + PDFEPub access policyFull text in EPub is free except for the current issue. Access to the latest issue is reserved only for the paid subscribers.View issue as eBookIssue statisticsRSSHide all abstracts Show selected abstracts Export selected to Add to my listEDITORIALScientistic reductionism and the "dark side"...
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Moyamoya disease: Girish Menon, Ajay HegdeArchives of Medicine and Health Sciences 2019 7(2):224-232Moyamoya disease (MMD) is a unique cerebrovascular disease characterized initially by an obliterative vasculopathy followed by a compensatory proliferative vasculopathy. Coined by Suzuki and Takaku in 1969, the term moyamoya (MM) refers to a "puff of smoke" like appearance of small collaterals seen traversing the basal ganglia and thalamus, in response to progressive stenosis and occlusion of supraclinoid...
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"When," "What," and "How" of complementary feeding: A mixed methods cross-sectional study from a rural medical college in central India: Priyanka A Joshi, Shiv H Joshi, Abhishek V RautArchives of Medicine and Health Sciences 2019 7(2):217-223Background and Aim: Undernutrition among under-five children is one of the most important public health problems in India. Despite several years of efforts to tackle undernutrition, India has not been able to make any significant dent on proportion of undernutrition....
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Effect of exposure to formaldehyde on the forced vital capacity of medical students: A longitudinal study: Dipak Kumar Dhar, Sudeepa ChaudhuriArchives of Medicine and Health Sciences 2019 7(2):212-216Background and Aim: Formaldehyde exposure is one of the various occupational hazards experienced by a doctor during his life. There is consistent and regular exposure to formaldehyde during the gross anatomy dissection classes. Since it vaporizes at room temperature, respiratory system is easily affected....
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Effect of exposure to formaldehyde on the forced vital capacity of medical students: A longitudinal study: Dipak Kumar Dhar, Sudeepa ChaudhuriArchives of Medicine and Health Sciences 2019 7(2):212-216Background and Aim: Formaldehyde exposure is one of the various occupational hazards experienced by a doctor during his life. There is consistent and regular exposure to formaldehyde during the gross anatomy dissection classes. Since it vaporizes at room temperature, respiratory system is easily affected....
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Does Thyroid dysfunction correlates with iron overload in Eβ thalassemia patients? A study from a tertiary care thalassemia center in India: Shuvraneel Baul, Tuphan Kanti Dolai, Pranab Kumar Sahana, Rajib De, Prakas Kumar Mandal, Prantar ChakrabartiArchives of Medicine and Health Sciences 2019 7(2):206-211Background and Aim: Large number of Haemoglobin E-beta thalassaemia (Hb E/β-thalassaemia) patients show iron overloads and related end-organ damage irrespective of transfusion requirements. The...
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Vascular malformation of the upper lip: Imran Mohtesham, Chethana Pillappa, Priyal RohanArchives of Medicine and Health Sciences 2019 7(2):258-261Vascular anomalies account as one among the most difficult diagnostic and therapeutic enigmas that can be encountered in the practice of medicine. These lesions are the result of an embryonic abnormality of the vascular system. The main characteristic feature of vascular malformations is that they never show the signs of involution. It is the most common...
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Profile of nutritional anemia and its correlation with serum iron, Vitamin B12, and folic acid level among the tribal population of northern districts of West Bengal, India: Ankita Dhanuka, Bidyut Krishna Goswami, Sarama Banerjee Goswami, Sudipta ChakrabartiArchives of Medicine and Health Sciences 2019 7(2):201-205Background and Objective: Nutritional anemia is the most common and easily preventable cause of anemia. No comprehensive data regarding the magnitude of this problem are available in the...
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Chronic sclerosing osteomyelitis: A case report on a rare complication of tooth extraction: Valen Dela D'souza, Elvita Martis, Kora Ramya Reddy, Prasanna Kumar Rao, Ritesh KB, Raghavendra Kini, Suraj HegdeArchives of Medicine and Health Sciences 2019 7(2):251-253Chronic osteomyelitis can be a protracted disease often caused by inadequate curettage, injudicious use of antibiotics, and unnecessary delay in treating infected teeth. Failure of treatment of the odontogenic infection may result in decreased...
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Alcohol dependence syndrome in suicide attempters: A cross-sectional study in a rural tertiary hospital: P Sreelatha, G Haritha, V S. S R. Ryali, Ryali P JanakiramanArchives of Medicine and Health Sciences 2019 7(2):195-200Background: Suicidal attempt is a phenomenon with a tremendous impact on the medical and social well-being of the individual, and alcohol abuse/dependence has consistently been implicated in the triggering of suicidal attempt. This complex interaction of alcohol and suicide needs...
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Airway concerns in a neonate with Treacher Collins syndrome posted for tracheoesophageal fistula repair: Sushama Raghunath Tandale, Yogesh Gavali, Subhadra Sinha, Chandraprabhu BirnaleArchives of Medicine and Health Sciences 2019 7(2):319-320Sir,A 3-day-old male, term neonate, weighing 2.9 kg was referred to our institute for tracheoesophageal fistula repair with provisional diagnosis of Treacher Collins syndrome More Details (TCS). Examination revealed tachypnea, heart rate 160 bpm, blood pressure...
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Peripheral blood level of natural killer cells in pregnant women with recurrent spontaneous abortion during the 6–12 weeks gestation: Sung-Guk Kim, Mi-Yong Paek, Il Gyong KoArchives of Medicine and Health Sciences 2019 7(2):191-194Background and Aim: The study was performed to confirm the clinical characteristics and peripheral blood level of natural killer (NK) cells as a diagnostic index in women with recurrent spontaneous abortion (RSA) comparing with normal pregnant women. Materials and Methods:...
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Childhood blistering distal dactylitis: An uncommon cutaneous manifestation of Staphylococcus aureus
Childhood blistering distal dactylitis: An uncommon cutaneous manifestation of Staphylococcus aureus: Maqbool Saep, Malcolm Pinto, Sateesh K MalkappaArchives of Medicine and Health Sciences 2019 7(2):309-310Blistering distal dactylitis (BDD) is a rare, bacterial skin infection presenting as bullous lesions over the fingers, especially in the age group of <16 years. We present a case of a child presenting with BDD secondary to Staphylococcus aureus infection.A 6-year-old girl was brought to the...
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Laryngeal manifestation due to smoking among the pediatric age group – Our experiences at an Indian teaching hospital: Santosh Kumar Swain, Ishwar Chandra Behera, Jatindra Nath MohantyArchives of Medicine and Health Sciences 2019 7(2):186-190Background and Aim: Smoking among the pediatric age group is a public health concern. It has direct link to laryngeal manifestations. Due to increased exposure to smoking, it is affecting the children directly or indirectly through involving upper airway, particularly...
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Epilepsy surgery in India: George C VilanilamArchives of Medicine and Health Sciences 2019 7(2):287-292The history of epilepsy surgery dates back to the era before computerized tomography, magnetic resonance imaging (MRI), positronemission tomogram imaging, and electroencephalogram (EEG). Victor Horsley's resection of a cortical scar in 1886, based purely on localization is considered as the first epilepsy surgery recorded in history. In India, Prof. Jacob Chandy performed a pediatric hemispherotomy...
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Mélange of orbital lesions – A histomorphologic study of 135 cases: Rashi Gupta, Suguna Belur Venugopal, Aparna Muralidhar, V Geethamani, Ankit MalhotraArchives of Medicine and Health Sciences 2019 7(2):181-185Background: The orbit is an important site for primary and secondary diseases. Various tissue types such as osseous, vascular, neural, muscular, and glandular may be involved with specific pathologies. Tumors can secondarily invade the orbit from the periorbital regions including the paranasal...
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Expression of c-Met in Primary and Recurrent Hepatocellular Carcinoma: Background:The clinical course of hepatocellular carcinoma (HCC) is complicated, because it often recurs and shows multiple lesions, some of which progress to a more malignant form, shortening the life of the patient. The hepatocyte growth factor receptor c-Met has been shown to play an important role in the pathogenesis of HCC, but the influence of c-Met expression on the clinical course of HCC remains to be fully elucidated....
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Molecular Barcode Sequencing for Highly Sensitive Detection of Circulating Tumor DNA in Patients with Esophageal Squamous Cell Carcinoma: Introduction:Next-generation sequencing (NGS) with molecular barcodes (MB) is a novel method that enables the highly sensitive detection of circulating tumor DNA (ctDNA) in a relatively wide range of genes. Objective:The aim of this study was to examine the utility of NGS with MB for detecting ctDNA in patients with esophageal squamous cell carcinoma (ESCC). Methods:Five...
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A Rare Case of Plasma Cell Gingivitis with Cheilitis: Background. Plasma cell gingivitis (PCG) is a rare condition of the gingiva, characterized histopathologically by infiltration of plasma cells in connective tissue. Hypersensitivity reaction due to antigen is considered as primary etiological factor. Case Presentation. The present case is of an 18-year-old male patient suffering from gingival enlargement along with cheilitis. Histopathological and immunohistochemistry of tissue revealed lesion...
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Epstein-Barr virus-positive diffuse large B cell lymphoma, not otherwise specified, carrying a t(19;22)(q13;q11) translocation: References1.Castillo JJ, Beltran BE, Miranda RN et al (2018) EBV-positive diffuse large B-cell lymphoma, not otherwise specified: 2018 update on diagnosis, risk-stratification and management. Am J Hematol 93:953–962CASArticleGoogle Scholar2.Martin-Subero JI, Ibbotson R, Klapper W et al (2007) A comprehensive genetic and histopathologic analysis identifies two subgroups of...
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Misfolding linked mutations of SERPINA1 gene are uncommon in preeclampsia: Chandrakala Nagarajappa, Sheela Shikaripur Rangappa, Sharath BalakrishnaArchives of Medicine and Health Sciences 2019 7(2):177-180Background: Alpha-1 antitrypsin (A1AT) is a protease inhibitor that plays an important role in regulating oxidative stress in preeclampsia (PE). Recent studies have shown that A1AT is misfolded in PE. However, the cause of A1AT misfolding is not known. Mutations in SERPINA1 gene is an established...
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Ophthalmological perspectives of toxic epidermal necrolysis: Gayatree Mohanty, Shovna Dash, Manoj Kumar, Devanshi DesaiArchives of Medicine and Health Sciences 2019 7(2):254-257Toxic epidermal necrolysis (TEN) is as rare as two cases per million per year, but the ocular manifestations and sequelae are very severe. We present a case series of seven patients admitted to the intensive care unit in a tertiary hospital with a diagnosis of TEN describing the extent of ocular involvement, its response to...
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Prevalence and distribution of dental agenesis among orthodontic patients of Kathmandu, Nepal: Sanjay Prasad Gupta, Shristi RauniyarArchives of Medicine and Health Sciences 2019 7(2):172-176Background: Tooth agenesis is the most common developmental dental anomaly in humans with a wide variability of distribution among different population. Objective: The objective of this study was to find out the prevalence of dental agenesis among Nepalese orthodontic patients of Kathmandu and its occurrence with...
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Intracranial hypertension secondary to levofloxacin-therapy: Jamir Pitton Rissardo, Ana Letícia Fornari CapraraArchives of Medicine and Health Sciences 2019 7(2):313-316Idiopathic intracranial hypertension (ICH) is characterized by elevated intracranial pressure without an evident etiology. Here, we report the case of an adult male who presented with headache, diplopia, blurred vision, and nausea. The patient stated that he had searched a general practitioner 1 week ago because he had experienced...
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Enterococcicidal activity of chlorine dioxide and lemon extract endorse them as contemporary root canal irrigants: Ramamurthi Arularasi Aberna, G Mohan, S SaranyaArchives of Medicine and Health Sciences 2019 7(2):167-171Background and Objective: Enterococcus faecalis offers challenges when present in an anatomically challenging and inaccessible site such as root canal and are instrumental in treatment failures. This emphasizes the need for irrigants besides mechanical instrumentation in root canal...
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Gilles de la Tourette syndrome: An overview: Andrea Nani, Andrea E CavannaArchives of Medicine and Health Sciences 2019 7(2):277-283Gilles de la Tourette syndrome (GTS) is a neurodevelopmental condition characterized by multiple motor and vocal tics with a chronic course. With its multifaceted range of symptoms, GTS lies at the crossroads of neurology and psychiatry. This review article provides an outline of GTS, encompassing its extended clinical phenomenology, pathophysiology, and treatment options....
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Lactate dehydrogenase and maternal and perinatal outcome in preeclamptic women: Simmi Kharb, N Bhandari, A Singh, A GuptaArchives of Medicine and Health Sciences 2019 7(2):163-166Background: Preeclampsia is a condition that is characterized by hypertension and proteinuria occurring after 28 weeks of gestation. It complicates 5%–8% of all pregnancies. Lactate dehydrogenase (LDH) is an intracellular enzyme and its level is increased in preeclamptic women due to cellular death. Preeclampsia is a multisystem...
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Scientistic reductionism and the "dark side" of modern medicine: A personal reflection: Bhaskara P ShelleyArchives of Medicine and Health Sciences 2019 7(2):139-150It is reasonable to expect the doctor to recognize that science may not have all the answers to problems of health and healing.– Norman CousinsOpinions cannot survive if one has no chance to fight for them.– Thomas Mann A Prologue: Ancient Wisdom of Science and Health in Indian Medicine Top"Open-minded people don't care to be right,...
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Cyberchondria: Implications of online behavior and health anxiety as determinants: Denelle Mohammed, Sara Wilcox, Camille Renee, Christine Janke, Niki Jarrett, Anjelika Evangelopoulos, Chasity Serrano, Nazmin Tabassum, Natashia Turner, Melody Theodore, Aleksandar Dusic, Rana ZeineArchives of Medicine and Health Sciences 2019 7(2):154-162Background: Cyberchondria is excessive worrying about one's health that develops following internet search for medical and health information. Aim: This study investigates...
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Giant cell tumor tendon sheath at inguinal region masquerading as enlarged lymph node: Minakshi Chouhan, Sheetal Arora, Neetika Gupta, Rashmi AroraArchives of Medicine and Health Sciences 2019 7(2):262-264Giant cell tumor of the tendon sheath (GCTTS) is a benign tumor and is the second most common tumor of the hand after ganglion cysts. It is a slow-growing benign lesion of the soft tissues. The etiology of GCTTS is not clear. Although GCTTS most commonly presents in a digit of the hand, it may also...
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Recurrent choroid plexus carcinoma: Ravi C Ambalath, Meher L Konatam, Stalin Bala, Sadashivudu GundetiJournal of Dr. NTR University of Health Sciences 2019 8(4):286-289Plexus-chorioideuscarcinomataor malignant plexus papillomas are very rare malignancy; only few cases have been described in the literature. A 2.5-year-old girl, known case of choroid plexus carcinoma, presented with complaints of weakness of right upper limb and lower limb, decreased activity, altered sensorium and vomiting. After...
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New simple unicortex locking intramedullary fixation of forearm shaft fracture: A Case report: Hyon-Chol Kim, Hak-Su KimJournal of Dr. NTR University of Health Sciences 2019 8(4):264-267We have used nonlocking nails in patients with small intramedullary canals for the fixation of segmental fractures of the radius and ulna. We report a patient with the Monteggia fracture dislocation (the ulnar shaft segmental fracture) treated by new simple unicortex locking intramedullary fixation.
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Poisoned to paralysed: A case of organophosphate induced delayed neuropathy: Mahadevaiah Mahesh, Sindhu Rao Malla, Chilkunda Raviprakash Venkatesh, Varsha TandureJournal of Dr. NTR University of Health Sciences 2019 8(4):281-283Organophosphate (OP) compound poisoning is a global public health problem and is a social calamity, especially in a developing country like India. Acute cholinergic crisis and intermediate syndrome after OP compound consumption are well-known and well-documented. Delayed neurological...
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Cystic lateral neck mass: Papillary thyroid carcinoma metastases with concomitant lymphangioma: Chitturi Ramya, Sripriya Krishnan, Inuganti Venkata Renuka, Sowjanya Krishna Sree KesaboyinaJournal of Dr. NTR University of Health Sciences 2019 8(4):261-263The most common presentation of papillary carcinoma thyroid is a solitary thyroid nodule but it is also known to present as cystic metastatic deposits in the neck. It has an indolent course and good prognosis. Although ultrasound is a commonly used...
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A rare case of rickettsial infection presented as febrile delirium in a 4 years old child from a government hospital, Andhra Pradesh, India: G S Rama Prasad, Suhasini Mekala, Naresh GadaganiJournal of Dr. NTR University of Health Sciences 2019 8(4):272-275We report here a documented case of Febrile delirium in a child caused by Rickettsiae. Rickettsial infection is a relatively under-diagnosed entity in children with fever and rash, probably due to low index of suspicion and the lack of definitive...
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Hemodialysis arteriovenous fistula maturation and role of perioperative vascular mapping: Ramesh Dasari, Siva Parvathi Karanam, Anil Kumar, A Tyagi, Siva Kumar, AY LakshmiJournal of Dr. NTR University of Health Sciences 2019 8(4):257-260Introduction: The arteriovenous fistula (AVF) is the preferred access in patients starting on maintenance hemodialysis. The vasculature of the upper limb has a dominant role in determining the successful outcome of AVF surgery. Hence, we aimed to determine the various...
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"A study on association of epstein barr virus in oral squamous cell carcinoma using polymerase chain reaction technique.": M Mary Prathyusha, Kiran K Kattappagari, Deepika Chowdary, Poosarla C Shekar, Dasarathi Alivelu, Baddam V R. ReddyJournal of Dr. NTR University of Health Sciences 2019 8(4):233-237Background and Aims: Head and neck cancer is the most common type of cancer in word wide and Oral squamous cell carcinoma (OSCC) accounts for 90% of oral cancers and it represents the sixth most frequent...
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The role of FNAC in diagnostically challenging malignant lesions of breast: Rajyalakshmi Rallapalli, Lakshmi V Chavali, Bhaskar V Rani, Ramana V Kada, Beulah P MaddiralaJournal of Dr. NTR University of Health Sciences 2019 8(4):250-256Background: Fine needle aspiration cytology is a simple investigation to evaluate the malignant tumors of the breast when compared to tru-cut biopsy. It is invaluable in the diagnosis of the common invasive carcinoma of the breast including its subtypes. The morphology...
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An unusual presentation of infrarenal aortoiliac occlusion with metastatic gas gangrene: J Abdul Gafoor, O Joji Reddy, D Harinath, N BhavanaJournal of Dr. NTR University of Health Sciences 2019 8(4):276-280Gas gangrene is a term reserved for fulminant soft tissue infections caused by Clostridium species. The posttraumatic form of gas gangrene is caused by Clostridium perfringens. Nontraumatic, or spontaneous, gas gangrene is even more rare and is usually caused by Clostridium septicum in two-thirds...
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Antimicrobial efficacy of herbal extracts combined with zinc oxide eugenol as an obturating material in primary teeth – An in vitro study: Senapathi Navaneet, Sridhar Muktineni, Sai Sankar J. Avula, Pranitha Kakarla, Harish C Kommineni, K AmruthavalliJournal of Dr. NTR University of Health Sciences 2019 8(4):244-249Background and Aims: The aim of this study is to evaluate the antimicrobial efficacy of synthetic obturating material (Zinc oxide eugenol) individually and combined with medicinal plant...
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Complete androgen insensitivity syndrome: A case report: Suresh K JariwalaJournal of Dr. NTR University of Health Sciences 2019 8(4):284-285Technology cannot replace clinical acumen. Think of complete androgen insensitivity syndrome (CAIS) in a female child with inguinal hernia. Diagnosis was missed in our patient when she presented with inguinal hernia the first time. Karyotyping should be done. Sex of rearing in CAIS is female. Chances of tumor development in retained testis are low. Testis helps...
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Cost-Effectiveness of Extended and One-Time Screening Versus No Screening for Non-Valvular Atrial Fibrillation in the USA: AbstractBackgroundThere is limited evidence on the clinical and cost benefits of screening for atrial fibrillation (AF) with electrocardiogram (ECG) in asymptomatic adults.MethodsWe adapted a previously published Markov model to evaluate the clinical and economic impact of one-time screening for non-valvular AF (NVAF) with a single 12-lead ECG and a 14-day extended screening...
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Mutant C9orf72 human iPSC‐derived astrocytes cause non‐cell autonomous motor neuron pathophysiology: Main pointsHuman iPSC‐derived astrocytes harboring C9orf72 mutations recapitulate key aspects of ALS pathology and cause non‐cell autonomous pathophysiology in human iPSC‐derived motor neurons. The pathophysiology induced in motor neurons by ALS astrocytes is characterized by a progressive loss of action potential output due to a decrease in voltage‐gated sodium and potassium currents. CRISPR/Cas9...
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Late‐onset interstitial nephritis in a patient with drug‐induced hypersensitivity syndrome/drug reaction with eosinophilia and systemic symptoms: AbstractDrug‐induced hypersensitivity syndrome (DIHS), also referred to as drug reaction with eosinophilia and systemic symptoms (DRESS), is a severe hypersensitivity drug reaction affecting the skin and multiple internal organ systems. We report a 47‐year‐old man with DIHS/DRESS and comorbidities (fulminant type 1 diabetes mellitus, valsartan‐induced photosensitivity,...
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Concomitant BRAF Mutation in Hairy Cell Leukemia and Papillary Thyroid Cancer: Case Report: Hairy cell leukemia (HCL) is rare type of leukemia. This neoplasm is well-known to present with pancytopenia and splenomegaly. HCL is associated with BRAF mutation in 100% of cases. It is also associated with hematological and oncological malignancies such as melanoma and papillary thyroid cancer. Although the association of both cancers (HCL and papillary thyroid cancer) with BRAF mutation is well established...
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Multimodal Treatment of Extragonadal Choriocarcinoma with Multiple Brain and Lung Metastases: A Case Report: Choriocarcinoma is a highly aggressive germ cell tumor and can metastasize to the brain. Although brain metastasis has a poor prognosis, the optimal treatment strategy remains unclear due to its low incidence. A 33-year-old man presenting with multiple lung nodules on chest radiography was referred to our hospital. Computed tomography revealed bilateral lung nodules and a large pelvic mass,...
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Complete laparoscopic duodenojejunostomy for superior mesenteric artery syndrome: Linear stapled closure of the common enterotomy: AbstractSuperior mesenteric artery syndrome can lead to duodenal obstruction due to vascular compression. We treated a patient with superior mesenteric artery syndrome by performing a complete laparoscopic duodenojejunostomy with a linear stapled closure of the common enterotomy. A 72‐year‐old woman presented with nausea, vomiting, and weight loss. CT revealed superior...
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Comparison of Ziehl-Neelsen's stain, fluorescent stain with CBNAAT of sputum for the diagnosis of pulmonary tuberculosis: Goteti V Padmaja, Kasukurthi Srujana, Chittari SadhanaJournal of Dr. NTR University of Health Sciences 2019 8(4):238-243Introduction: Pulmonary tuberculosis remains one of the most dangerous communicable diseases. More than two billion people are estimated to be infected with Mycobacterium tuberculosis. In 2017, approximately 10 million individuals became ill with tuberculosis,among...
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Pleomorphic adenoma of soft palate with extensive squamous metaplasia – A diagnostic enigma: Rashmi Patnayak, Sandip Mohanty, Anjan Kumar Sahoo, Adya Kinkara Panda, Amitabh JenaJournal of Dr. NTR University of Health Sciences 2019 8(4):268-271Pleomorphic adenoma is the most common salivary gland tumor. It can have a wide range of morphological spectrum. But extensive squamous metaplasia mimicking squamous cell carcinoma is quite uncommon. Palate is a common site for minor salivary gland tumor. Less...
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Safety and efficacy of VB-111, an anti-cancer gene-therapy, in patients with recurrent glioblastoma: results of a phase I/II study: AbstractBackgroundVB-111 is a non-replicating adenovirus carrying a Fas-chimera transgene, leading to targeted apoptosis of tumor vascular endothelium and induction of a tumor specific immune response. This phase I/II study evaluated the safety, tolerability and efficacy of VB-111 with and without bevacizumab in recurrent glioblastoma (rGBM).MethodsPatients with rGBM...
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A randomized controlled phase III study of VB-111 combined with bevacizumab vs. bevacizumab monotherapy in patients with recurrent glioblastoma (GLOBE): AbstractBackgroundOfranergene obadenovec (VB-111) is an anti-cancer viral therapy that demonstrated in a Phase-II study a survival benefit for patients with recurrent glioblastoma (rGBM) who were primed with VB-111 monotherapy that was continued after progression with concomitant bevacizumab.MethodsThis pivotal phase-III randomized, controlled trial...
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A new detection method for EMG activity monitoring: AbstractThis paper introduces a new approach for electromyography (EMG) activity monitoring based on an improved version of the adaptive linear energy detector (ALED), a widely used technique in voice activity detection. More precisely, we propose a modified ALED technique (named M-ALED) to improve the method's robustness with respect to noise. To achieve this objective, M-ALED relies on the Teager-Kaiser operator for signal pre-conditioning to...
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Quality of life in the FOXFIRE, SIRFLOX, and FOXFIRE‐Global randomised trials of selective internal radiotherapy for metastatic colorectal cancer: Selective internal radiotherapy (SIRT) is a liver‐directed treatment involving injection of yttrium‐90 microspheres in to the blood supply of liver tumours. There are very few studies assessing health related quality of life (HRQOL) in patients treated with SIRT. Patients with liver metastases from colorectal cancer (CRC) were randomised in the FOXFIRE...
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CTLA4 blockade promotes vessel normalization in breast tumors via the accumulation of eosinophils: Immune checkpoint blockade (ICB) has shown long‐term survival benefits, but only in a small fraction of cancer patients. Recent studies suggest that improved vessel perfusion by ICB positively correlates with its therapeutic outcomes. However, the underlying mechanism of such process remains unclear. Here, we show that anti‐cytotoxic T‐lymphocyte‐associated protein 4 (CTLA4) treatment‐induced tumor...
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A Biomimicking Polymeric Cryogel Scaffold for Repair of Critical-Sized Cranial Defect in a Rat Model
A Biomimicking Polymeric Cryogel Scaffold for Repair of Critical-Sized Cranial Defect in a Rat Model: Tissue Engineering Part A, Volume 25, Issue 23-24, Page 1591-1604, December 2019. AbstractMineralized polymeric cryogels with interconnective macroporous structure have demonstrated their potential as promising scaffolding material in bone tissue engineering. However, their capability in inducing osteogenic differentiation of mesenchymal stem cells (MSCs) in vitro and osteogenesis in vivo has not...
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Reinforcing the primary immunotherapy modulators against acute leukemia; monoclonal antibodies in AML: Immunotherapy, Ahead of Print. Recent therapeutic advances in cancer treatment recruit immune system potentiation against malignant cells. Numerous ongoing clinical trials on immunotherapy methods, either monotherapy or combination therapy, are investigating the impeding factors on the way of acute myeloid leukemia (AML) treatment. Due to the genetic diversity in AML progenitors, combining various...
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Elevated Levels of Platelet Activating Factor and Its Acetylhydrolase Indicate High Risk of Kawasaki Disease: Journal of Interferon &Cytokine Research, Ahead of Print. AbstractKawasaki disease (KD) is a systemic vasculitis in children, which is related to inflammation and abnormal activation of immune system. Platelet activating factor (PAF) and its acetylhydrolase (PAF-AH) may play an important role in the pathogenesis of KD. This study aimed to investigate diagnosis and prognostic value of...
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Copper-induced oxidative stress, initiation of antioxidants and phytoremediation potential of flax ( Linum usitatissimum L.) seedlings grown under the mixing of two different soils of China: AbstractFlax (Linum usitatissimum L.), one of the oldest cultivated crops, continues to be widely grown for oil, fiber and food. Furthermore, the plants show a metal tolerance dependent on species so is ideal for research. Present study was conducted to find out the influence of copper (Cu) toxicity on plant...
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Industrial water pollution and transboundary eco-compensation: analyzing the case of Songhua River Basin, China: AbstractAs eco-compensation is considered an effective economic instrument for controlling the industrial water pollution in transboundary basin, this study aims to explore a transboundary eco-compensation mechanism for Songhua River Basin that is one of the seven major drainage basins in China. Using a panel dataset of eleven cities in this basin tracked from 1992 to 2016, we empirically...
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'I will do my very best!' Children who engage in positive self-talk about effort can boost their math achievement: (Society for Research in Child Development) Children who think poorly of themselves often underachieve in school. A new Dutch study tested whether a simple mental activity -- having children with low self-confidence say favorable, encouraging words to themselves -- could boost their achievement. The study found that children who engaged in this kind of self-talk improved their math performance...
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Canalis Sinuosus Damage after Immediate Dental Implant Placement in the Esthetic Zone: Dental implant failure in the anterior maxilla can be caused by the range of the features. One of them is neighboring neurovascular structure damage, such as the canalis sinuosus (CS), that carries the superior anterior alveolar nerve. The aim of the report is to demonstrate clinical symptomatology and radiographic signs of CS damage in a 45-year-old female patient who underwent upper left lateral incisor extraction...
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Urotensin-II-Targeted Liposomes as a New Drug Delivery System towards Prostate and Colon Cancer Cells: Urotensin-II (UT-II) and its receptor (UTR) are involved in the occurrence of different epithelial cancers. In particular, UTR was found overexpressed on colon, bladder, and prostate cancer cells. The conjugation of ligands, able to specifically bind receptors that are overexpressed on cancer cells, to liposome surface represents an efficient active targeting strategy to enhance selectivity and...
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Recovering of Dizziness of a Patient with Sinusitis after Root Canal Therapy for Upper Second Molar: This case report illustrates the recovery of dizziness of a young healthy patient after root canal therapy of upper second molar. The patient developed dizziness and unbalanced walking four months ago. After cardiac, ENT, neurological, physiotherapy and medical investigations, his entire checkup showed no abnormalities. The patient visited a dental clinic for a routine checkup; after dental clinical...
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Continuous Professional Oral Health Care Intervention Improves Severe Aspiration Pneumonia: Professional oral health care (POHC) is known to prevent aspiration pneumonia in patients with dysphagia and/or those at the perioperative stage of surgery. However, the effect of POHC on patients suffering from aspiration pneumonia remains unknown. Here, we report a case where continual POHC intervention improved severe aspiration pneumonia. A 74-year-old male patient with a brain infarction suffered from...
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One-year outcome of coenzyme Q10 supplementation in ADCK3 ataxia (ARCA2): AbstractBackgroundThe recessive ataxia ARCA2 is a rare disorder characterized by Coenzyme Q10 (CoQ10) deficiency due to biallelic mutations in ADCK3 gene. Despite the pathophysiological role, available data are not univocal on clinical efficacy of CoQ10 supplementation in ARCA2. Here we described the long-term motor outcome of 4 untreated ARCA2 patients prospectively followed-up for one year after starting CoQ10 oral supplementation...
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Radiological and toxicity risk exposures of oil based mud: health implication on drilling crew in Niger Delta: AbstractNaturally occurring radioactive materials (NORMs) and the presence of toxic metals in drilling fluids/their additives have raised research interests in recent times owing to the risks associated with the exposure times for drillers of petroleum wells. In this study, two drilling fluids A and B were formulated, while two other Mud Samples C and D were obtained from drilled shale and...
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Recommended care and care adherence following a diagnosis of Lynch syndrome: a mixed-methods study: AbstractBackgroundLynch syndrome (LS) is the most common hereditary colorectal cancer (CRC) syndrome. This study assesses trends in diagnosis of LS and adherence to recommended LS-related care in a large integrated healthcare organization (~ 575,000 members).MethodsElectronic medical record (EMR) data (1999–2015) were examined to identify patients with a diagnosis of LS. We examined their LS-associated...
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Patients with pathogenic variants for breast cancer other than BRCA1 and BRCA2: qualitative interviews about health care experiences: AbstractBackgroundGenetic testing for hereditary cancer syndromes has been revolutionized by next-generation sequencing, which allows for simultaneous review of numerous genes. Multigene panels are regularly offered to patients because of their scope and decreased cost and turnaround time. However, many genes included on larger panels have not been studied as extensively...
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Toxicity testing in the 21st century: progress in the past decade and future perspectives: AbstractAdvances in the biological sciences have led to an ongoing paradigm shift in toxicity testing based on expanded application of high-throughput in vitro screening and in silico methods to assess potential health risks of environmental agents. This review examines progress on the vision for toxicity testing elaborated by the US National Research Council (NRC) during the decade that has passed since the...
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Idiopathic nephrotic syndrome and serum permeability factors: a molecular jigsaw puzzle: AbstractNephrotic syndrome is traditionally defined using the triad of edema, hypoalbuminemia, and proteinuria, but this syndrome is very heterogeneous and difficult to clarify. Its idiopathic form (INS) is probably the most harmful and essentially comprises two entities: minimal change disease (MCD) and focal segmental glomerulosclerosis (FSGS). We will consider some hypotheses regarding the mechanisms underlying...
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Plakophilins and their roles in diseased states: AbstractTissue homeostasis is maintained by several cellular mechanisms and an imbalance may lead to diseased states. Here, the plakophilins 1, 2 and 3 operate as structural components and stabilize desmosomal cell-cell contacts. In their non-junctional states, they serve as regulators of signaling programs and control varied cellular processes that range from transcription, mRNA abundance, protein synthesis, growth, proliferation, migration to invasion...
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Arsenic-Containing Qinghuang Powder (青黄散) is an Alternative Treatment for Elderly Acute Myeloid Leukemia Patients Refusing Low-Intensity Chemotherapy: AbstractObjectiveTo analyze the overall survival (OS) of elderly acute myeloid leukemia (AML) patients treated with oral arsenic-containing Qinghuang Powder (青黄散, QHP) or low-intensity chemotherapy (LIC).MethodsForty-two elderly AML patients treated with intravenous or subcutaneous LIC (1 month for each course, at least 3 courses) or oral QHP (3 months...
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Reducing avoidable chest pain admissions and implementing high-sensitivity troponin testing: NHS accident and emergency departments see 0.5 million patients presenting with a cardiac condition each year. The accurate assessment of chest pain and subsequent diagnosis or exclusion of myocardial infarction (MI) represent a significant challenge, with important consequences on patient outcome and healthcare resources. We conducted a cross-sectional analysis of patients admitted with cardiac chest pain...
08:53
Canadian duo invent a toothpaste tablet to eliminate plastic tubes: "Toothpaste tubes take over 500 years to break down and are unable to be recycled. We've developed toothpaste tablets that remove the need for a tube altogether.": submitted by /u/mvea [link] [comments]
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An anomalous case of the flexor carpi radialis with an excessive muscular bundle: AbstractA variation of the flexor carpi radialis with an excessive muscular bundle was found on the right forearm of a Japanese male cadaver. The flexor carpi radialis had two heads, medial one arising from the medial epicondyle of the humerus, and the other, a variant excessive muscular bundle, arising from the bicipital aponeurosis deep at the medial edge of the tendon of biceps brachii. There was also a muscular...
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Saccharomyces boulardii reduces the mean intensity of infection in mice caused by the consumption of liver contaminated by Toxocara canis: AbstractProbiotics have shown promising results as a potential method to control toxocariasis in mice inoculated with embryonated eggs of Toxocara canis. This study aimed to evaluate the protective effect of Saccharomyces boulardii in mice fed in natura chicken livers infected with T. canis. Twenty 15-day-old male Sussex chickens were inoculated with 300 T. canis...
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Harper's Textbook of Pediatric Dermatology, 2 Volume Set, 4th Edition: A consummate classic with a fresh approach to pediatric dermatologyChildren´s skin is different. Maturation affects the epidermal barrier, the cutaneous microbiome, adnexal structures, vasculature, and transcutaneous absorption of drugs. The immature skin is more susceptible to pathogens and environmental disruption. Many genetic disorders are either present at birth or manifest early in childhood. Skin diseases thus present...
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Pharmacoepidemiology, 6th Edition: This classic, field-defining textbook, now in its sixth edition, provides the most comprehensive guidance available for anyone needing up-to-date information in pharmacoepidemiology. This edition has been fully revised and updated throughout and continues to provide a rounded view on all perspectives from academia, industry and regulatory bodies, addressing data sources, applications and methodologies with great clarity.Read More...
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Exosomal miRNA Let-7 from Menstrual Blood-Derived Endometrial Stem Cells Alleviates Pulmonary Fibrosis through Regulating Mitochondrial DNA Damage: Idiopathic pulmonary fibrosis (IPF) is a prototype of chronic, progressive, and fibrotic lung disease with high morbidity and high mortality. Menstrual blood-derived stem cells (MenSCs) have proven to be an attractive tool for the treatment of acute lung injury and fibrosis-related diseases through immunosuppression and antifibrosis. However, whether...
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Is Movember synonymous with moustaches or men's health? An examination of internet search activity for prostate and testicular cancer during the campaign.: Is Movember synonymous with moustaches or men's health? An examination of internet search activity for prostate and testicular cancer during the campaign.Ir J Med Sci. 2019 Dec 14;:Authors: Khan JS, Papa NP, Davis NF, Wrafter PF, Kelly JC, Dowling CM, D'Arcy FTAbstract BACKGROUND: The Movember campaign encourages men to grow a moustache...
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Effects of bamboo shoots (Bambusa balcooa) on thyroid hormone synthesizing regulatory elements at cellular and molecular levels in thyrocytes.: Related ArticlesEffects of bamboo shoots (Bambusa balcooa) on thyroid hormone synthesizing regulatory elements at cellular and molecular levels in thyrocytes.J Ethnopharmacol. 2019 Dec 12;:112463Authors: Sarkar D, Chandra AK, Chakraborty A, Ghosh S, Chattopadhyay S, Singh LH, Ray IAbstract ETHNOPHARMACOLOGICAL RELEVANCE: Bamboo shoots (BS) are consumed...
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Copaiba oleoresin has topical antinociceptive activity in a UVB radiation-induced skin-burn model in mice.: Related ArticlesCopaiba oleoresin has topical antinociceptive activity in a UVB radiation-induced skin-burn model in mice.J Ethnopharmacol. 2019 Dec 12;:112476Authors: Becker G, Brusco I, Casoti R, Lay Marchiori MC, Cruz L, Trevisan G, Oliveira SMAbstract ETHNOPHARMACOLOGICAL RELEVANCE: Copaiba oleoresin, extracted from Copaifera L., is used as a wound healing, analgesic, antimicrobial...
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Efficacy and safety of indigo naturalis ointment in Treating Atopic Dermatitis: A randomized clinical trial.: Efficacy and safety of indigo naturalis ointment in Treating Atopic Dermatitis: A randomized clinical trial.J Ethnopharmacol. 2019 Dec 12;:112477Authors: Lin YK, Chang SH, Yang CY, See LC, Lee BH, Shih IHAbstractETHNOPHARMACOLOGICAL RELEVANCE: Indigo naturalis, a herbal medicine with a history of use dating back to ancient times, may be a good alternative topical treatment for atopic dermatitis...
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The Matrisome during Aging and Longevity: A Systems-Level Approach toward Defining Matreotypes Promoting Healthy Aging.: Related ArticlesThe Matrisome during Aging and Longevity: A Systems-Level Approach toward Defining Matreotypes Promoting Healthy Aging.Gerontology. 2019 Dec 13;:1-9Authors: Ewald CYAbstract Accumulation of damage is generally considered the cause of aging. Interventions that delay aging mobilize mechanisms that protect and repair cellular components. Consequently, research...
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Prevalence of hypohydration and its association with stroke severity and independence outcomes in acute ischemic stroke patients.: Related ArticlesPrevalence of hypohydration and its association with stroke severity and independence outcomes in acute ischemic stroke patients.J Clin Neurosci. 2019 Dec 11;:Authors: Buoite Stella A, Gaio M, Furlanis G, Ridolfi M, Ajčević M, Sartori A, Caruso P, Morrison SA, Naccarato M, Manganotti PAbstract Hypohydration has been suggested increasing the risk...
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Common Regulatory Targets of NFIA, NFIX and NFIB during Postnatal Cerebellar Development.: Related ArticlesCommon Regulatory Targets of NFIA, NFIX and NFIB during Postnatal Cerebellar Development.Cerebellum. 2019 Dec 14;:Authors: Fraser J, Essebier A, Brown AS, Davila RA, Harkins D, Zalucki O, Shapiro LP, Penzes P, Wainwright BJ, Scott MP, Gronostajski RM, Bodén M, Piper M, Harvey TJAbstract Transcriptional regulation plays a central role in controlling neural stem and progenitor cell proliferation...
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Opsoclonus Following Downbeat Nystagmus in Absence of Visual Fixation in Multiple System Atrophy: Modulation and Mechanisms.: Related ArticlesOpsoclonus Following Downbeat Nystagmus in Absence of Visual Fixation in Multiple System Atrophy: Modulation and Mechanisms.Cerebellum. 2019 Dec 14;:Authors: Lee JY, Kwon E, Kim HJ, Choi JY, Oh HJ, Kim JSAbstract We report atypical opsoclonus in a patient with multiple system atrophy and propose a mechanism based on the patterns of modulation by visual,...
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Cells with ganglionic differentiation frequently stain for VE1 antibody: a potential pitfall.: Related ArticlesCells with ganglionic differentiation frequently stain for VE1 antibody: a potential pitfall.Brain Tumor Pathol. 2019 Dec 09;:Authors: Tan CL, Lian DWQ, Kuick CH, Chan YH, Chang KTEAbstract Mitogen-activated protein kinase (MAPK) pathway plays a major role in pediatric low-grade gliomas (pLGGs). Immunohistochemistry with mutant-specific antibody, VE1, has appeared to be the most...
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Assessment of the contralateral facial artery pedicle nasolabial island flap for buccal defect repair: Publication date: Available online 15 December 2019Source: International Journal of Oral and Maxillofacial SurgeryAuthor(s): X. Zhou, S.-E. Zhang, P. Nueangkhota, Y.-J. Liang, Y.-X. Su, G.-Q. LiaoAbstractThe facial artery pedicle nasolabial island flap (FAPNIF) is widely used for oral and maxillofacial reconstruction. However, its use in reconstruction after malignant tumour resection is limited...
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In vitro compressive strength and edge stability testing of directly repaired glass-ionomer cements: AbstractObjectiveTo study the repair potential of seven commercial glass-ionomer cements (GICs) using an in vitro edge compression test model.Materials and methodsA total of 448 normal and 192 repaired cylindrical specimens (6 × 4 mm) were produced from 6 GICs and one resin-modified GIC. Repaired samples consisted of a base aged for 1 month before repaired by an overlying layer. All samples were matured...
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Endoscopic transnasal transmaxillary approach to the upper parapharyngeal space and the skull base: AbstractPurposeTreatment of tumors arising in the upper parapharyngeal space (PPS) or the floor of the middle cranial fossa is challenging. This study aims to present anatomical landmarks for a combined endoscopic transnasal and anterior transmaxillary approach to the upper PPS and the floor of the middle cranial fossa and to further evaluate their clinical application.MethodsDissection of the upper...
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Feasibility of 3D printed salivary duct models for sialendoscopic skills training: preliminary report: AbstractPurposesTo explore the feasibility of 3D printed salivary duct models for the sialendoscopic skills training.MethodsHealthy volunteers and patients affected by obstructive salivary gland disorders were submitted to 3 Tesla MR sialography. The MR data underwent an image segmentation process to produce the 3D printed salivary duct prototypes. Sialendoscopies were carried out by three groups...
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Hearing screenings for preschool children: A comparison between whispered voice and pure tone audiogram tests.: Related ArticlesHearing screenings for preschool children: A comparison between whispered voice and pure tone audiogram tests.Int J Pediatr Otorhinolaryngol. 2019 Nov 27;130:109798Authors: Skoloudik L, Mejzlik J, Janouch M, Drsata J, Vodicka J, Chrobok VAbstract INTRODUCTION: This prospective study compares the efficiency of two hearing screening tests performed on preschool children....
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Selenium improves photosynthesis and induces ultrastructural changes but does not alleviate cadmium-stress damages in tomato plants: AbstractThe application of Se to plants growing under Cd contamination may become an alternative strategy to minimize Cd damage. However, there is no specific information available regarding whether Se can affect the anatomical structure and photosynthetic rates of plants under Cd stress. To address questions related to Se-protective responses under Cd stress, we evaluated...
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Is topical fluorescein that effective in endoscopic CSF leak closure?: AbstractPurposeSeveral diagnostic modalities are used to detect CSF leaks. Intraoperative use of intrathecal fluorescein can help to detect and localize a CSF leak simultaneously. However, it is not FDA approved, the application is invasive and has serious complications. Topical fluorescein is reported to be a safe and sensitive alternative to ITF. In this study, we aimed to evaluate the effectiveness of topical fluorescein in...
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Patient-recorded benefit from nasal closure in a Danish cohort of patients with hereditary haemorrhagic telangiectasia: AbstractBackgroundNasal closure, also known as the modified Young's procedure was introduced in Denmark in 2008, as a surgical solution to severe epistaxis in patients with hereditary haemorrhagic telangiectasia (HHT). The objective of this study was to report the overall satisfaction of the procedure from a patient's point of view as well as the occurrence of complications.MethodsAll...
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A comparison of international clinical practice guidelines on adult chronic rhinosinusitis shows considerable variability of recommendations for diagnosis and treatment: AbstractObjectivesTo compare international clinical practice guidelines on adult chronic rhinosinusitis (CRS).DesignExtensive literature search in Embase, PubMed and the internet (Google, websites of well-known guideline organizations) on November 21st 2018.Main outcome measuresGuidelines' quality was measured by the AGREE II instrument....
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Pre- and intraoperative acoustic and functional assessment of the novel APrevent ® VOIS implant during routine medialization thyroplasty: AbstractPurposePersistent unilateral vocal fold paralysis (UFVP) with glottal insufficiency often requires type I medialization thyroplasty (MT). Previous implants cannot be adjusted postoperatively if necessary. The newly developed APrevent® VOIS implant (VOIS) can provide postoperative re-adjustment to avoid revision MT. The objective of this pilot study is to...
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Diagnosis and management of septal deviation and nasal valve collapse - a survey of Canadian otolaryngologists: AbstractBackgroundManagement of nasal valve collapse (NVC) in patients with a septal deviation can be challenging. Our objective was to determine the opinions of Canadian Otolaryngologists regarding the diagnosis and management of nasal obstruction in patients with septal deviation and NVC.MethodsA twenty-question survey was developed for the purpose of our study. Questions were divided...
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Intersegmenter Variability in High‐Speed Laryngoscopy‐Based Glottal Area Waveform Measures: Objectives/HypothesisHigh‐speed videoendoscopy (HSV) has potential to objectively quantify vibratory vocal fold characteristics during phonation. Glottal Analysis Tools (GAT) version 2018, developed in Erlangen, Germany, is software for determining various glottal area waveform (GAW) quantities. Before having GAT analyze HSV videos, segmenters have to define glottis manually across videos in a semiautomatic...
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Manifestations of Skull Base IgG4‐Related Disease: A Multi‐Institutional Study: ObjectiveIgG4‐related disease (IgG4‐RD) is a recently recognized disease characterized by fibroinflammatory infiltrates rich in IgG4+ plasma cells that can present as isolated tumor‐like lesions of the head and neck. The objective of the current study was to describe the cranial base manifestations of IgG4‐RD.MethodsReview of all cases at three tertiary‐referral centers since disease description in 2003.ResultsEleven...
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Manifestations of Skull Base IgG4‐Related Disease: A Multi‐Institutional Study: ObjectiveIgG4‐related disease (IgG4‐RD) is a recently recognized disease characterized by fibroinflammatory infiltrates rich in IgG4+ plasma cells that can present as isolated tumor‐like lesions of the head and neck. The objective of the current study was to describe the cranial base manifestations of IgG4‐RD.MethodsReview of all cases at three tertiary‐referral centers since disease description in 2003.ResultsEleven...
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Endoscopic Nasopharyngectomy Combined with a Nerve‐sparing Transpterygoid Approach: Objectives/HypothesisSurgical management of nasopharyngeal tumors has evolved in the endoscopic era. Lateral exposure remains difficult especially near the petrous internal carotid artery and bony Eustachian tube (ET). Our study examines the need to sacrifice the vidian and greater palatine nerves in order to successfully perform en bloc endoscopic nasopharyngectomy.MethodsFour cadaveric specimens (eight sides) were...
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Gallic acid affects blood-brain barrier permeability, behaviors, hippocampus local EEG, and brain oxidative stress in ischemic rats exposed to dusty particulate matter: AbstractDust storms are environmental natural events that transport high concentrations of particulate matter (PM) in living spaces. Recent epidemiological studies have shown that air pollution is associated with stroke. In the present study we aimed to investigate the probable protective effects of gallic acid (GA) on blood-brain...
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Ethnopharmacological Potentials of Warburgia ugandensis on Antimicrobial Activities: AbstractWarburgia ugandensis (W. ugandensis) is known by various names, including the East African greenheart, pepper bark tree, and Ugandan greenheart, and has a rich history of extensive use in the treatment of a host of human diseases in many African countries. This review is based on the botany and ethnopharmacological potentials of W. ugandensis for the treatment of pneumonia, asthma, malaria, candidiasis, skin...
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Identification of Key Genes and Signaling Pathways Associated with the Progression of Gastric Cancervia http://link.springer.com/search.rss?facet-content-type=Article&facet-journal-id=12253&channel-name=Pathology+%26+Oncology+ResearchAbstractGenomic features have been gradually regarded as part of the fundamentals to the clinical diagnosis and treatment for gastric cancer. However, the molecular alterations taking place during the progression of gastric cancer remain unclear. Therefore,...
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Morphological and Molecular Characteristics of the Gastro-Intestinal Nematode Parasite Ascaridia columbae Infecting the Domestic Pigeon Columba livia domestica in Saudi ArabiaAbstractBackgroundParasitism is a complex problem that is often ignored in companion animals, including birds, unless it develops into a severe clinical disorder. The present study was, therefore, aimed to investigate the presence of the gastrointestinal nematode infecting the domestic pigeon and provide a complete morphological...
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Letter to the Editor on the Article: "Mixed Reality Anatomy Using Microsoft HoloLens and Cadaveric Dissection: a Comparative Effectiveness Study"Integration of Basic and Clinical Sciences: Student PerceptionsAbstractThe integrated curriculum is becoming a popular concept among dental schools. The purpose of this study was to query dental students at the University of Texas Health Science Center at Houston – School of Dentistry (UTSD) to elucidate their level of interest in the integrated curriculum,...
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Review of Outcome Measures in Trials and Practice for PsoriasisAbstractPurpose of ReviewThe purpose of this review was to determine the most frequently utilized outcome measures in clinical trials and to review the scoring criteria, advantages, disadvantages, and application in research and clinical settings, as well as provide an overview of the published guidelines on the use of outcome measures in clinical practice.Recent FindingsThe most frequently utilized physician-reported outcome measurement...
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Mitochondrial dysfunction in heart failure. Lessons from a hereditary mitochondrial diseaseThe voyage: Amalgating a social media platform through the annual scientific meetingAbstractSocial media platforms are increasingly used by professional societies for improved member engagement, to raise awareness, for advocacy and for widespread dissemination of scientific meeting highlights. This article describes the inaugural social media campaign implemented at the American Society of Nuclear Cardiology...
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The development of competency frameworks in healthcare professions: a scoping reviewAbstractCompetency frameworks serve various roles including outlining characteristics of a competent workforce, facilitating mobility, and analysing or assessing expertise. Given these roles and their relevance in the health professions, we sought to understand the methods and strategies used in the development of existing competency frameworks. We applied the Arksey and O'Malley framework to undertake this scoping...
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Giving ThanksNo abstract availableCorneal Endothelial Blebs Induced in Scleral Lens WearersSIGNIFICANCE In the bleb phenomenon, some endothelial cells transiently lose their specular reflection. This has been reported during contact lens wear and goggle-induced hypoxia or hypercapnia. PURPOSE The purposes of this study were to determine whether blebs appear after scleral lens wear and if their appearance is influenced by lens clearance and to compare bleb and cell sizes. METHODS Twenty-one subjects...
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Effects of Self-selected or Predetermined Intensity Aerobic Exercise on the Quality of Life of Adolescents with ObesityThis study aimed to compare the effects of aerobic training at self-selected intensity (SIE) and predetermined intensity (PIE) on the health-related quality of life (HRQOL) in adolescents with obesity. Randomized clinical trial conducted with 37 adolescents (boys and girls), 13–18 yr old, at Tanner stages 3–4, and body mass index ≥95th. Eighteen adolescents were randomly assigned...
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Award-Winning Study Highlights a Pivotal Question: Why is Disc Degeneration Sometimes Painful?No abstract availableDrive-by Billing CrisisNo abstract availableParalyzed Man Uses Brain Waves to Power an External SkeletonNo abstract availableNew Recommendations on Osteoporotic Fractures: Do Conflicts of Interest Impair Their Credibility?No abstract availableThe Burnout Crisis Demonstrates the Need for Broad Cultural Change in the Practice of MedicineNo abstract availableWhat About Coaching to Prevent...
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Surgical Outcomes and Quality Assessment of Trabeculectomy: Leveraging Electronic Health Records for Clinical Data VisualizationPrécis: This electronic medical record-based study demonstrates 1 approach to monitor clinical outcomes for individual physicians performing trabeculectomy. Purpose: The purpose of this study was to develop an interactive data visualization platform for evaluating trabeculectomy outcomes and monitoring clinical care quality. Patients and Methods: This is a retrospective...
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Effectiveness of acupuncture for the treatment of postoperative pain: A protocol for a systematic review of randomized controlled trialBackground: This aim of this study is to assess the effectiveness and safety of acupuncture for the treatment of patients with postoperative pain (PPP). Methods: We will carry out a systematic review of the published literature and will comprehensively search Cochrane Library, MEDLINE, EMBASE, CINAHL, PsycINFO, Allied and Complementary Medicine Database, Chinese Biomedical...
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A Winter's TaleNo abstract availableKnee Replacement Patients May Enjoy Life-Changing Surgical Outcomes With RSIP Vision's Revolutionary Artificial Intelligence SolutionNo abstract availableFood and Drug Administration Issues Important New GuidanceNo abstract availableInterpretation of Codes and StandardsNo abstract availableLigature Risk Management and Medical EquipmentNo abstract availableSeven Maryland and Virginia Municipalities Receive Grants For Policy and Environmental Changes that Promote...
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An Update to Changing Patterns of Anal Carcinoma in the United StatesObjectives: Approximately 8,300 new cases of anal carcinoma will be diagnosed in the United States in 2019. Anal squamous cell carcinoma (SCC) accounts for about 70% of all anal cancers. As cancer prevention and treatments have evolved over time, medical management of human immunodeficiency virus has improved, and sexual behaviors have changed, anal carcinoma incidence rates (IRs) may have also changed. Methods: The 9 oldest Surveillance,...
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OnlineFirstLast updated December 16, 2019 1 – 100 of 371Sort:ClinicOpen AccessDouble Ring in Cochlear Otosclerosis: A Limit to Cochlear Implantation? The Solution Is the Surgical ApproachDaniela Messineo, MD, Massimo Ralli, MD, PhD, Antonio Greco, MD, Arianna Di Stadio, MD, PhDFirst Published 16 Dec 2019.https://doi.org/10.1177/0145561319895601AbstractHide PreviewWe present a case of a 50-year patient with a severe form of otosclerosis (double ring) that was successfully implanted. We used a bone-anchored...
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Electron Tomography Revels that Milk Lipids Originate from Endoplasmic Reticulum Domains with Novel Structural FeaturesAbstractLipid droplets (LD) are dynamically-regulated organelles that originate from the endoplasmic reticulum (ER), and function in the storage, trafficking and metabolism of neutral lipids. In mammary epithelial cells (MEC) of lactating animals, intact LD are secreted intact into milk to form milk lipids by a novel apocrine mechanism. The secretion of intact LD and the relatively...
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Vital Data: Re/Introducing Historical BioarchaeologyColonialism, Community, and Heritage in Native New EnglandChallenging Colonial Narratives: Nineteenth-Century Great Lakes ArchaeologyWar at Sea: A Shipwrecked History from Antiquity to the Twentieth CenturySubmerged History: Underwater Archaeology in FloridaFramings of Capitalism and the Archaeology of Sugar in the Islamic MediterraneanAbstractSeeking to widen the constellation of pasts in studies of capitalism, this article contributes to interventions...
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Original ResearchNo AccessPrevalence of Pediatric Dizziness and Imbalance in the United StatesJacob R. Brodsky, MD, Sophie Lipson, Neil Bhattacharyya, MDFirst Published 5 Nov 2019.https://doi.org/10.1177/0194599819887375AbstractHide PreviewObjectivesUnderstand the prevalence of vestibular symptoms in US children.Study DesignCross-sectional analysisSetting2016 National Health Interview Survey.Subjects and MethodsResponses from the 2016 National Health Interview Survey for children ages 3 to 17 years...
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Original ResearchNo AccessPsychometric Evaluation of the Nasal Obstruction Symptom Evaluation Scale for Pediatric PatientsHena Din, MPH, Nour Bundogji, Shelby C. Leuin, MDFirst Published 10 Dec 2019.https://doi.org/10.1177/0194599819890835AbstractHide PreviewObjectiveTo evaluate the psychometric properties of the nasal obstruction symptom scale within a sample of pediatric patients undergoing septoplasty or functional septorhinoplasty.Study DesignThis was a prospective study with nasal obstruction...
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Hena Din, MPH, Nour Bundogji, Shelby C. Leuin, MDFirst Published 10 Dec 2019.https://doi.org/10.1177/0194599819890835AbstractHide PreviewObjectiveTo evaluate the psychometric properties of the nasal obstruction symptom scale within a sample of pediatric patients undergoing septoplasty or functional septorhinoplasty.Study DesignThis was a prospective study with nasal obstruction symptom scale evaluations conducted pre- and postoperatively.SettingA tertiary care pediatric hospital.Subjects and MethodsPediatric...
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Value-Enhancing Social Responsibility: Market Reaction to Donations by Family vs. Non-family Firms with Religious CEOsAbstractUsing a signaling framework, we argue that ethical behavior as evidenced by charitable donations is viewed more positively by investors when seen not to be based on self-serving motives but rather on authentic generosity that builds moral capital. The affirmed religiosity of CEOs may make their ethical position more credible, while their embeddedness within a family business...
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Holmium laser lithotripsy improves the rate of successful transcystic laparoscopic common bile duct explorationAbstractPurposeTranscystic laparoscopic common bile duct exploration (LCBDE) seems safer than transductal LCBDE and is associated with fewer biliary complications. It has traditionally been limited to smaller bile duct stones however. This study aimed to assess the ability of laser-assisted bile duct exploration by laparoendoscopy (LABEL) to increase the rate of successful transcystic LCBDE...
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Phytochemicals enriched in spices: a source of natural epigenetic therapyAbstractMetabolic disorders are increasing at an alarming rate due to the stressful lifestyle and inappropriate diet schedule. The unorganized habits influence multiple epigenetic mechanisms like DNA methylation, histone post-translational modifications and miRNA expression. These epigenetic modifications are reversible in nature and regulate gene expression in response to external stimuli without altering the DNA sequence....
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Three-Dimensional Porous Trabecular Scaffold Exhibits Osteoconductive Behaviors In VitroAbstractIn the USA, approximately 500,000 bone grafting procedures are performed annually to treat injured or diseased bone. Autografts and allografts are the most common treatment options but can lead to adverse outcomes such as donor site morbidity and mechanical failure within 10 years. Due to this, tissue engineered replacements have emerged as a promising alternative to the biological options. In this study,...
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Endoscopic full-thickness resection for a duodenal gastrointestinal stromal tumourPublication date: Available online 6 December 2019Source: Arab Journal of GastroenterologyAuthor(s): Xiang-lei Yuan, Xiao-wei Liu, Bing HuDrug-induced pancreatitis: An updatePublication date: Available online 2 December 2019Source: Arab Journal of GastroenterologyAuthor(s): Jie Zheng, Qiu-Jin Yang, Fu-Tao Dang, Jing YangAbstractDrug-induced pancreatitis is a disease that is receiving increasing attention. This article...
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Therapeutic hypothermia and acute brain injuryPublication date: Available online 12 December 2019Source: Anaesthesia & Intensive Care MedicineAuthor(s): Jagdish Sokhi, Ugan ReddyAbstractSecondary brain injury has devastating effects on morbidity, mortality and good functional outcomes. Neuroprotection is multimodal, with decades of preclinical and small clinical studies showing the benefits of therapeutic hypothermia. The basic scientific principles have merit, yet large randomized controlled...
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Successful Verbal Communication Using Google Translate to Facilitate Awake Intubation of a Patient With a Language Barrier: A Case ReportPerioperative difficult airway management is one of the most challenging tasks encountered by anesthesiologists. Awake intubation is considered the gold standard in securing the anticipated difficult airway. Effective communication between the anesthesiologist and patient is vital during awake intubation. A language barrier can significantly hinder success and jeopardize...
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select article Corrigendum to "Cutaneous keratinocyte cancers of the head and neck: Epidemiology, risk factors and clinical, dermoscopic and reflectance confocal microscopic features" [Oral Oncol. 98 (2019) 109–117] ErratumFull text access Corrigendum to "Cutaneous keratinocyte cancers of the head and neck: Epidemiology, risk factors and clinical, dermoscopic and reflectance confocal microscopic features" [Oral Oncol. 98 (2019) 109–117] Katie J. Lee, Mitchell Robinson, H. Peter SoyerIn Press, Corrected...
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select article Complications of bone-conduction hearing implants implantation surgeryResearch articleAbstract onlyComplications of bone-conduction hearing implants implantation surgeryTimothy Shun Man Chu, Michael Mather, Anirvan BanerjeeIn Press, Journal Pre-proof, Available online 16 December 2019Purchase PDFArticle previewAbstractAbstractPurposeBone-conduction Hearing Implants (BCHIs) are surgically implanted hearing devices. As the implantation surgery involves soft tissue dissection through...
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Management of recurrent and metastatic oral cavity cancer: Raising the bar a step higherPublication date: February 2020Source: Oral Oncology, Volume 101Author(s): Petr Szturz, Jan B. VermorkenAbstractIn recurrent and/or metastatic squamous cell carcinoma of the head and neck (R/M-SCCHN), the armamentarium of systemic anti-cancer modalities continues to grow in parallel with innovations in and better integration of local approaches. The backbone of cytotoxic chemotherapy remains cisplatin with 5-fluorouracil...
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